中国医学科学院学报2017，Vol.39Issue(2)：206-210,5.DOI:10.3881/j.issn.1000-503X.2017.02.007
122例朗格汉斯细胞组织细胞增生症临床分析
Clinical Analysis of 122 Cases of Langerhans Cell Histiocytosis
王涛 1苏蓓蓓 1韩大伟 2童安莉 1李剑 3刘跃华 4晋红中 1方凯1
作者信息
- 1. 中国医学科学院北京协和医学院北京协和医院皮肤科,北京100730
- 2. 新乡市中心医院皮肤科,河南新乡453000
- 3. 中国医学科学院北京协和医学院北京协和医院内分泌科,北京100730
- 4. 中国医学科学院北京协和医学院北京协和医院血液内科,北京100730
- 折叠
摘要
Abstract
Objective To investigate the features of Langerhans cell histiocytosis (LCH).Method Skin lesions,systemic involvement,imaging characteristics,laboratory tests,immunophenotying,treatment response,and survival of 122 LCH patients treated at our center from February 1983 to August 2013 were retrospectively analyzed.Results LCH was associated with diverse skin lesions.Lung was the most involved organ,followed by bone,skin,lymph nodes,liver,spleen,oral cavity,and thyroid.Multisystem LCH was more common than single-system LCH.Single-system LCH was mostly treated by surgery,whereas multisystem LCH by combined chemotherapy.Conclusions LCH has diverse clinical manifestations,with lungs being the most often involved organ.Surgery or chemotherapy is the mainstream treatment.关键词
朗格汉斯细胞组织细胞增生症/临床分析/回顾性/治疗Key words
Langerhans cell histiocytosis/clinical analysis/retrospective/treatment分类
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王涛,苏蓓蓓,韩大伟,童安莉,李剑,刘跃华,晋红中,方凯..122例朗格汉斯细胞组织细胞增生症临床分析[J].中国医学科学院学报,2017,39(2):206-210,5.
