中国医学装备2017，Vol.14Issue(7)：72-75,4.DOI:10.3969/J.ISSN.1672-8270.2017.07.018
功能磁共振成像对针刺联合中医药治疗脑梗死疗效评价
Evaluation of fMRI functional imaging in the curative effect of the acupuncture combined with traditional Chinese medicine in the treatment for patient with cerebral infarction
摘要
Abstract
Objective: To explore the relationship between the combinative intervention therapy and clinical curative effect, through used function magnetic resonance imaging (fMRI) to observe the change of detection data for patients with cerebral infarction pre and post-intervention therapy of acupuncture combined with traditional Chinese medicine (TCM). Methods: 40 patients with cerebral infarction were divided into control group (20cases, received normal treatment)and observation group (20cases, received combinative treatment of acupuncture and TCM). Pre and post therapy, the patients of every group received evaluation about state of illness and detection of fMRI. The score of national institute of health stroke scale (NIHSS) was used to evaluate the degree of neurologic impairment, and analyze the imaging manifestations of fMRI on patients with cerebral infarction at basal ganglia who received acupuncture combined with TCM. Some cerebral functional imaging techniques, included blood oxygenation level dependent( BOLD), fMRI and diffusion tensor imaging (DTI), were used to grasp the changes of relevant functional region of brain and different brain regions connected with function region of patients with cerebral infarction before and after therapy. Results: The NIHSS score of observation group was significantly less than that of the control group (t=5.450, P<0.05), and the total efficiency of observation group (95%) was significantly higher than that of the control group (75%) (x2=4.329, P<0.05). And the differences of the activation frequency, activation volume, ADCavg values and the values of FA between the observation group and the control group were statistically significant (t=5.425, 2.760, 3.453, 5.513, P<0.05). Conclusion: Acupuncture combined with traditional Chinese medicine can efficiently improve the status of neurologic impairment for patients with cerebral infarction, and the clinical efficacy before and after treatment can preferably be observed by fMRI.关键词
脑梗死/功能磁共振成像(fMRI)/针刺/中药/临床疗效Key words
Cerebral infarction/functional magnetic resonance imaging (fMRI)/Acupuncture/Traditional Chinese medicine/Clinical efficacy分类
医药卫生引用本文复制引用
赵波沣,胡元明,陈树平..功能磁共振成像对针刺联合中医药治疗脑梗死疗效评价[J].中国医学装备,2017,14(7):72-75,4.基金项目
深圳市卫计委2015年基金项目(201501039)"fMRI功能成像对脑梗塞针药结合治疗前后对比研究" （201501039）
