中国药业2017，Vol.26Issue(13)：39-41,3.DOI:10.3969/j.issn.1006-4931.2017.13.012
胸腔微创置管辅助尿激酶或链激酶注入治疗结核性胸膜炎临床评价
Clinical Evaluation of Minimally Invasive Thoracic Cavity Drainage Tube Combined with Urokinase or Streptokinase Injection in Treating Tuberculous Pleurisy
摘要
Abstract
Objective To investigate the curative effects of minimally invasive thoracic cavity drainage tube combined with urokinase or streptokinase injection in treating tuberculous pleurisy. Methods A total of 90 patients with tuberculous pleurisy were randomly divided into thoracic cavity drainage combined with urokinase group ( group UK ) , thoracic cavity drainage combined with streptokinase ( group SK ) and the control group ( group C ) , 30 cases in each group. The group C was only treated with routine anti-tuberculosis treatment and repeated thoracic puncture drainage, on this basis, the group UK and the group SK were treated with urokinase ( 25 millions IU ) or streptokinase ( 25 millions IU ) injected through thoracic cavity drainage. Results Compared with the group C, the total effective rate of the group UK and the group SK were obviously improved ( P < 0. 05 ) . In the UK group and the SK group, the times of thoracic puncture, the time of chest tightness and fever were significantly shortened, and the residual pleural thickness was significantly decreased ( P < 0. 05 ) . After treatment, the pulmonary function indexes and arterial blood gas analysis of the 3 groups were significantly improved than before treatment ( P < 0. 05 ) , but there was no significantly difference among the 3 groups ( P > 0. 05 ) . Compared with the group C, the pneumothorax, pleural reaction and bleeding in the group UK and the group SK were significantly lower ( P < 0. 05 ) . Conclusion Compared with repeatedly thoracentesis, injecting urinatese or streptokinase into chest by thoracic cavity drainage has better curative effect and less adverse reactions.关键词
胸腔微创置管/尿激酶/链激酶/结核性胸膜炎/疗效Key words
minimally invasive thoracic cavity drainage/urinatese/streptokinase/tuberculous pleurisy/clinical efficacy分类
医药卫生引用本文复制引用
林晔,李淳南,陈炀森..胸腔微创置管辅助尿激酶或链激酶注入治疗结核性胸膜炎临床评价[J].中国药业,2017,26(13):39-41,3.基金项目
广东省潮州市卫生和计划生育局科研项目[潮卫科研201462 ]. （）
