中国药业2017，Vol.26Issue(14)：4-6,3.DOI:10.3969/j.issn.1006-4931.2017.14.002
板蓝根水提液纳滤浓缩工艺研究
Nanofiltration Concentration Process of Aqueous Extract of Radix Isatidis
伍永富 1朱河澄 1冯天炯 2罗维早2
作者信息
- 1. 太极集团重庆中药二厂有限公司,重庆 402284
- 2. 太极集团有限公司,重庆 408000
- 折叠
摘要
Abstract
Objective To investigate the nanofiltration concentration process of aqueous extract of Radix Isatidis. Methods HPLC method was adopted to determine the retention rate of ( R,S ) epigoitrin with mobile phase of methanol-0. 02% the phosphoric acid so-lution ( 7:93 ) ,the detection wavelength was 245 nm. With the retention rate and membrane flux of ( R,S ) epigoitrin as the indexes,the effects of operating pressure,adsorption characteristics and other factors on concentration process were investigated by single factor tests. Results The retention rate of ( R,S ) epigoitrin increased with decreasing of aperture and unchanged with change of pressure and cycles of concentratin. Membrane flux was positively correlated with intercept relative molecular weight and pressure,decreased as con-centration ratioincreased. Retention rate of ( R,S ) epigoitrin was 97. 50% when nanofiltration membranes aperture was 200 Da. When the membrane flux was 60 L/ ( m2·h ) ,the process had no obvious influence to other ingredients in Radix Isatidis with high concentra-tion efficiency. Conclusion Nanofiltration concentration is suitable for concentrating liquid of Radix Isatidis,it has high efficiency and low losses of active ingredients.关键词
(R,S)告依春/纳滤工艺/膜通量/保留率Key words
( R,S ) epigoitrin/nanofiltration process/membrane flux/retention rate分类
化学化工引用本文复制引用
伍永富,朱河澄,冯天炯,罗维早..板蓝根水提液纳滤浓缩工艺研究[J].中国药业,2017,26(14):4-6,3.
