中国真菌学杂志2017，Vol.12Issue(3)：162-167,6.
NLRP3炎症小体与真菌感染
The effects of NLRP3 inflammasome in fungal infection
摘要
Abstract
In fungal infection,host immune cells recognized pathogen associated molecular patterns (PAMPs),such as beta glucan,by pattern recognition receptors (PRRs) and trigger innate immunity against fungi.NLRP3,a member of NLR family,together with ASC and caspase-1,constituting NLRP3 inflammasome,participated in or controls fungal infection.In this paper,we reviewed the role of NLRP3 inflammasome in the fungal infection in recent years.关键词
白念珠菌/NLRP3炎症小体/天然免疫/模式识别受体/病原体相关分子模式Key words
Candida albicans/NLRP3 inflammasome/innate immunity/pattern recognition receptors (PRRs)/pathogen associated molecular patterns (PAMPs)分类
医药卫生引用本文复制引用
徐志庆,吴大强,邵菁,汪天明,汪长中..NLRP3炎症小体与真菌感染[J].中国真菌学杂志,2017,12(3):162-167,6.基金项目
国家自然科学基金(81573725) （81573725）
