中国中医药信息杂志2017，Vol.24Issue(8)：89-92,4.DOI:10.3969/j.issn.1005-5304.2017.08.020
基于HPLC指纹图谱对救必应与其伪品的鉴别研究
Identification of Ilicis Rotundae Cortex and Its Adulterant Based on HPLC Fingerprint
摘要
Abstract
Objective To establish HPLC fingerprints for the identification of Ilicis Rotundae Cortex (Jiubiying), dried bark of Ilex rotunda Thunb., and its adulterant, dried bark of Ilex godajam (Colebr.) Wall.. Methods Some samples named "Jiubiying" were collected from some medicine markets and drugstores. The HPLC fingerprints were obtained to detect Jiubiying and Ilex godajam. The software "Similarity Evaluation System of Chromatographic Fingerprints of Traditional Chinese Medicine (2004A edition)" was used to evaluate fingerprints. Results The fingerprints of Jiubiying and Ilex godajam were established. Methodological study met the technical requirements of fingerprints. There were 31 and 28 common peaks in Jiubiying and Ilex godajam, respectively. Jiubiying and Ilex godajam could be classified into two clusters by principal component analysis and hierarchical clustering analysis. Conclusion Jiubiying and Ilex godajam can be identified by HPLC fingerprints. This method can provide an effective method for quality evaluation of Jiubiying.关键词
救必应/米碎木/高效液相色谱法/指纹图谱/主成分分析/质量控制Key words
Ilicis Rotundae Cortex (Jiubiying)/Ilex godajam (Colebr) Wall./HPLC/fingerprint/principal component analysis/quality control分类
医药卫生引用本文复制引用
马玉翠,王淳,王蔚,吴翠,杜宁,孙文,李慧,巢志茂..基于HPLC指纹图谱对救必应与其伪品的鉴别研究[J].中国中医药信息杂志,2017,24(8):89-92,4.基金项目
国家质量监督检验检疫总局行业科研专项(201210209) （201210209）
