中国卒中杂志2017，Vol.12Issue(7)：592-597,6.DOI:10.3969/j.issn.1673-5765.2017.07.006
Enterprise支架治疗复杂症状性颅内动脉粥样硬化性狭窄
Enterprise Stent in Treatment of Symptomatic Complex Intracranial Atherosclerotic Stenosis
刘恋 1缪中荣 1马宁 1莫大鹏 1高峰 1徐晓彤 1宋立刚 1孙瑄 1王博 1霍晓川1
作者信息
- 1. 首都医科大学附属北京天坛医院脑血管病中心,介入神经病学 北京 100050
- 折叠
摘要
Abstract
Objective To assess the feasibility and efficacy of Enterprise stent using in treatment of Symptomatic Complex Intracranial Atherosclerotic Stenosis (ICAS). Methods The data of 24 patients with symptomatic severe stenosis of a major intracranial artery refractory to aggressive medical therapy were treated by undersized balloon angioplasty and Enterprise stent deployment from January 2014 to June 2016 were collected. All the lesions were considered as complex ICAS, i.e. with tortuous access, long (>15 mm) lesions and/or arterial bifurcations, or with concurrent aneurysms near the stenotic lesion. The primary outcome was defined any stroke (including ischemic or hemorrhagic), transient ischemic attack (TIA) or deaths after stenting procedure within 30 days. The secondary outcome was successful revascularization;occurrence of >50% in-stent restenosis; or occurrence of TIA or stroke attributable to the target vessel during the follow-up. Results Of the 24 patients included, the 30-day stroke, TIA or death was 4.2% (1/24), which presented as asymptomatic subarachnoid hemorrhage (SAH). There was no ischemic complications occurred during or after procedures (0%) in this cohort. The procedural success rate of 100 %, and stenosis was reduced from (87.1±9.3)% to (17.5±8.7)%. Four concurrent aneurysms were embolized simultaneously. Eighteen patients underwent imaging follow-up and 6 patients (33.3%) developed in-stent restenosis (ISR) during 6-month angiographic follow-up. Among which, 3 patients had symptomatic restenosis and underwent in-stent ballon angioplasty. Conclusion In this study, undersized balloon angioplasty followed by Enterprise stent deployment appears technically feasibility with a relatively low rate of complications for the treatment of ICAS. Stent with catheter-delivery might promote the procedural safety.关键词
颅内动脉狭窄/介入治疗/Enterprise支架/血管成形Key words
Intracranial stenosis/Intervention therapy/Enterprise stent/Angioplasty引用本文复制引用
刘恋,缪中荣,马宁,莫大鹏,高峰,徐晓彤,宋立刚,孙瑄,王博,霍晓川..Enterprise支架治疗复杂症状性颅内动脉粥样硬化性狭窄[J].中国卒中杂志,2017,12(7):592-597,6.
