中国卒中杂志2017，Vol.12Issue(7)：609-613,5.DOI:10.3969/j.issn.1673-5765.2017.07.009
影响颈动脉粥样硬化易损斑块对称性分布的危险因素分析
Risk Factors Analysis for Symmetrical Distribution of Carotid Atherosclerotic Vulnerable Plaque
摘要
Abstract
Objective To investigate the risk factors affecting the symmetrical distribution of carotid atherosclerotic plaques. Methods A total of 81 patients with ischemic stroke patients were prospectively enrolled consecutively as the research subject, whom were performed with more comparative sequence, black blood and carotid artery high resolution magnetic resonance imaging (MRI). According to the results of MRI, the patients were divided into 3 groups with no high risk vulnerable plaque group (n=40), unilateral high risk vulnerable plaque group (n=26) and bilateral high risk vulnerable plaque group (n=15). The clinical data of age, sex, hypertension, diabetes, current smoking history, blood pressure value, pulse pressure, BMI index and blood lipid level etc. were recorded. Logistic regression analysis was used to analyze the risk factors for carotid artery vulnerable plaque formation. Results Single factor analysis showed that there were statistically significant differences in hypertension history, current smoking history, BMI and systolic pressure in three groups (P<0.05). Multi-factors Logistic regression analysis showed that current smoking history (OR 3.136, 95%CI 1.122-8.766, P=0.03) was an independent factor for the occurrence of high risk vulnerable plaque and its symmetrical distribution. Conclusion There is correlation between current smoking history and the symmetrical distribution of carotid plaque. Smoking cessation might be good for the stability of plaque.关键词
颈动脉/易损斑块/对称性分布/危险因素Key words
Carotid artery/Vulnerable plaque/Symmetrical distribution/Risk factors引用本文复制引用
米东华,赵锡海,龚浠平,董可辉,赵性泉,王春雪,王伊龙,王拥军,刘丽萍..影响颈动脉粥样硬化易损斑块对称性分布的危险因素分析[J].中国卒中杂志,2017,12(7):609-613,5.基金项目
国家自然科学基金青年项目(81601015)北京市优秀人才培养资助项目(2015000021469G220)天坛医院青年基金项目(2015-YQN-13) （81601015）
