中成药2017，Vol.39Issue(7)：1410-1414,5.DOI:10.3969/j.issn.1001-1528.2017.07.018
二十五味肺病丸质量标准的研究
Quality standard for Ershiwuwei Feibing Pills
摘要
Abstract
AIM To establish the quality standard for Tibeten medicine Ershiwuwei Feibing Pills [Inula racemosa Hook.f.,Swertia bimaculata (Sieb.et Zucc.) Hook.Thors.ex Clarke,Phyllanthus emblica Linn.,Terminalia billerica (Gaertn.) Roxb.,etc.].METHODS TLC was applied to the qualitative identification of L racemosa,S.bimaculata,P.emblica and T.billerica,and HPLC was adopted in the quantitative determination of alantolactone,oleanolic acid,gallic acid and hydroxysafflor yellow A.RESULTS The TLC spots were clear without negative interference.Alantolactone,oleanolic acid,gallic acid and hydroxysafflor yellow A showed good linear relationships within the ranges of 4.324-216.2 μg/mL (r =0.999 9),32.222-1 611.1 μg/mL (r =0.999 9),4.072-203.6 μg/mL (r =0.999 9) and 4.266-213.3 μg/mL (r =0.999 9),whose average recoveries (RSDs) were 100.6％ (0.93％),100.3％ (2.1％),101.5％ (3.0％) and 100.1％ (1.8％),respectively.CONCLUSION This simple method can be used for the rapid quality control of Ershiwuwei Feibing Pills.关键词
二十五味肺病丸/化学成分/TLC/HPLCKey words
Ershiwuwei Feibing Pills/chemical constituents/TLC/HPLC分类
医药卫生引用本文复制引用
李翔,刘亚丽,乔培,张婧,刘志青,黄琴,陈静,詹春凤..二十五味肺病丸质量标准的研究[J].中成药,2017,39(7):1410-1414,5.基金项目
国家自然科学基金(81603054,81560575) （81603054,81560575）
江西民族传统药现代科技与产业发展协同创新中心开放基金项目资助项目(JXXT201403013) （JXXT201403013）
江西省自然科学基金(20151BAB215040,20151BAB215038) （20151BAB215040,20151BAB215038）
“赣鄱英才555工程”项目(赣财教指[2013] 296) （赣财教指[2013] 296）
江西省博士后科研择优资助项目(2016KY08) （2016KY08）
2016年度省杰出青年人才资助计划(20162BCB23034) （20162BCB23034）
