浙江医学2017，Vol.39Issue(10)：797-800,后插2,5.DOI:10.12056/j.issn.1006-2785.2017.39.10.2017-245
小梁切除术对泪膜功能影响的研究
Effect of trabeculectomy on tear film function
摘要
Abstract
Objective To evaluate the tear film changes after trabeculectomy and to estimate the subjective symptoms using ocular surface disease index (OSDI).Methods Twenty five glaucoma patients undergoing trabeculectomy were recruited.OSDI score,first tear film break-up point,first and average non-invasive tear film break-up time (NITBUT) and tear meniscus height (TMH) were measured preoperatively,1,3 and 6 months postoperatively.Correlation between OSDI scores and the tear film parameters was analyzed.Results The preoperative and postoperative OSDI scores were significantly different(P＜ 0.01).Compared with pre-operation,OSDI scores of at 1m and 3m postoperatively were increased significantly (all P＜0.01),however,it was no significant different with that at 6m postoperatively (P ＞0.05).The first tear film break-up point was located most frequently at the inferonasal quadrant pre-operation and 1m postoperatively,but it was located at the supernasal quadrant at 3m and 6m postoperatively.The first NITBUT was decreased at 1m,3m and 6m postoperatively compared with pre-operation (P＜0.05).The average NITBUT at 1m and 3m postoperatively decreased significantly,but at 6m postoperatively showed no difference compared with pre-operation (P ＞0.05).There was no statistically significant difference between preoperative and postoperative TMH (P ＞0.05).OSDI scores showed negative correlation with NITBUT in each time point,and no significant correlation with TMH.Conclusion At 6 months after trabeculectomy,although the subjective symptoms scores are restored in glaucoma patients,however,the stability of tear film is still unrecovered and the first tear film break-up point is most frequently located at supernasal and supertemporal quadrant adjacent the filtering bleb.关键词
小梁切除术/泪膜/非侵入性泪膜破裂时间/中央泪河高度Key words
Trabeculectomy/Tear film/Non-invasive tear film break-up time/Tear meniscus height引用本文复制引用
聂莉,潘伟华,赵云娥,叶函,陈雪文..小梁切除术对泪膜功能影响的研究[J].浙江医学,2017,39(10):797-800,后插2,5.基金项目
温州市科技计划项目(Y20160463) （Y20160463）
浙江省医药卫生科技计划项目(2017KY496,2017KY490) （2017KY496,2017KY490）
