肿瘤防治研究2017,Vol.44Issue(6):437-441,5.DOI:10.3971/j.issn.1000-8578.2017.16.0904
肿瘤疫苗在肺癌治疗中的进展
Advances of Tumor Vaccine in Lung Cancer Therapy
摘要
Abstract
Lung cancer is the most commonly diagnosed cancer as well as the leading cause of cancer-related deaths worldwide.Traditional anti-tumor treatments,including surgery,chemotherapy and radiotherapy,have been maximized.Recent years,cancer immunotherapy has been shown a broad prospect.Low immunogenicity of tumor antigens,which can not cause the enough anti-tumor immunity,is one of the mechanisms of tumor immune escape.The tumor vaccination can clear or control the tumor by applying tumor cells or tumor antigens substance to induce specific cellular and humoral immune response,which enhances the body's anticancer ability,and prevents tumor growth,proliferation and recurrence.In this article,we systematically review the advances of vaccine therapy on lung cancer in recent years.关键词
肺癌/免疫治疗/肿瘤疫苗/黑色素瘤相关抗原A3/黏液性糖蛋白1Key words
Lung cancer/Immunotherapy/Tumor vaccines/MAGE-A3/MUC 1分类
医药卫生引用本文复制引用
刘华丽..肿瘤疫苗在肺癌治疗中的进展[J].肿瘤防治研究,2017,44(6):437-441,5.基金项目
国家自然科学基金(81372407) (81372407)