中药材2017，Vol.40Issue(2)：306-310,5.DOI:10.13863/j.issn1001-4454.2017.02.012
矿物药硼砂的X射线衍射与拉曼光谱鉴别
Identification of Mineral Chinese Medicine Borax by X-Ray Diffraction and Raman Spectrum
摘要
Abstract
Objective:To establish Raman spectral fingerprint of Borax,and to provide a new method for identification of Borax.Methods:Based on the accurate identifications of 13 batches of Borax samples with XRD technology,the Raman mean and median spectra of eight authentic Borax were established,and the common peaks of these eight Borax spectra and their mean and median spectra were determined and were used to establish Raman spectral fingerprint of Borax.Then,the similarity evaluation and cluster analysis were also used for estimating the performance of Raman spectral fingerprint.Results:The XRD analysis indicated that samples S1 ～ S8 were authentic Borax,and the rest were counterfeits.The Raman spectral fingerprint with ten common peaks of mean and median spectrum from eight Borax was established.According to the correlation for similarity evaluation,the correlation of the Borax was greater than 97％,and the correlation of counterfeits was less than 29％.Cluster analysis results also could accurately distinguish authenticity and counterfeit.Conclusion:Raman spectroscopy can be quickly and accurately used for the identification of Borax sample and its powder.关键词
硼砂/XRD/拉曼光谱/指纹图谱/相似度/聚类分析Key words
Borax/XRD/Raman Spectrum/Fingerprint/Similarity degree/Cluster analysis分类
医药卫生引用本文复制引用
崔晓慧,陈龙,陈科力..矿物药硼砂的X射线衍射与拉曼光谱鉴别[J].中药材,2017,40(2):306-310,5.基金项目
重大新药创制国家科技重大专项(2014ZX09304307001) （2014ZX09304307001）
