郑州大学学报（理学版）2017，Vol.49Issue(3)：99-103,5.DOI:10.13705/j.issn.1671-6841.2017013
新型丙烯酮类化合物的合成及其生物活性
Synthesis and Biological Activity of New Acrylic Ketone Derivatives
摘要
Abstract
Twelve new acrylic ketone derivatives were synthesized with chalcone as lead compounds and triazene as substituent.These compounds were characterized by 1HNMR,IR and MS.The results conformed well to the expected structures.Twelve new compounds were screened by MTT assay in vitro activity.It was discovered that all of these compounds had anti-cancer activity.关键词
丙烯酮类化合物/合成/生物活性Key words
acrylic ketone derivative/synthesis/biological activity分类
化学化工引用本文复制引用
魏光璞,毛若望,刘曼莉,李佳,张茜,龙跃..新型丙烯酮类化合物的合成及其生物活性[J].郑州大学学报（理学版）,2017,49(3):99-103,5.基金项目
河南省科技攻关计划项目(0624420031) （0624420031）
河南省基础研究基金项目(022463001) （022463001）
大学生创新创业训练计划项目(2016xjxm253). （2016xjxm253）
