重庆医学2017，Vol.46Issue(20)：2777-2779,3.DOI:10.3969/j.issn.1671-8348.2017.20.013
氢氯吡格雷联合尼膜同治疗短暂性脑缺血发作的临床效果分析
Analysis on clinical effect of clopidogrel hydrogen sulfate plus nimodipine in treating transient cerebral ischemic attack
李承科 1何琴 1谯飞 1付安辉 1唐辉1
作者信息
- 1. 川北医学院第二临床学院/四川省南充市中心医院神经外科 637000
- 折叠
摘要
Abstract
Objective To investigate the efficacy and safety of clopidogrel hydrogen sulfate plus nimodipine in treating transient cerebral ischemic attack.Methods A total of 159 outpatients and inpatients with transient cerebral ischemic attack in the neurosurgery department and the neurology outpatient department of our hospital from January 1,2012 to September 1,2016 were divided into 3 groups.The group A(43 cases) orally took clopidogrel hydrogen sulfate plus aspirin;the group B (51 cases) treated with oral clopidogrel hydrogen sulfate plus nimodipine;the group C(65 cases) was treated with clopidogrel hydrogen sulfate plus nimotop.The curative effects were observed in 3 groups.The differences of PT.APTT,FIB and PLT in 3 groups were compared between before and after treatment.Results The total effective rate of the group A and C was significantly better than that of the group B(P<0.05),the curative effect had no statistical difference between the group A and C (P>0.05);the effect of the group B and group C on coagulation was superior to that of the group A(P<0.05).The three group had no severe bleeding events(cerebral bleeding,etc.),the difference was statistically significant.Conclusion Clopidogrel hydrogen sulfate combined with nimotop can significantly reduce the frequency of transient cerebral ischemic attack,has little influence on the coagulation indicators,and is safe and effective.关键词
氢氯吡格雷/尼膜同/脑缺血发作/短暂性Key words
clopidogrel hydrogen sulfate/nimodipine/ischemic attack,transient分类
医药卫生引用本文复制引用
李承科,何琴,谯飞,付安辉,唐辉..氢氯吡格雷联合尼膜同治疗短暂性脑缺血发作的临床效果分析[J].重庆医学,2017,46(20):2777-2779,3.
