重庆医学2017，Vol.46Issue(21)：2921-2922,2926,3.DOI:10.3969/j.issn.1671-8348.2017.21.012
外用糖皮质激素联合夫西地酸乳膏对婴儿湿疹的干预作用
Interventional effect of topical corticosteroids combined with fusidic acid cream in infantile eczema
卢静静 1郑源泉 1付桂莉1
作者信息
- 1. 华中科技大学同济医学院附属武汉儿童医院/武汉市妇幼保健院皮肤科 430016
- 折叠
摘要
Abstract
Objective To investigate the clinical efficacy of topical corticosteroids combined with fusidic acid cream in treating infantile eczema.Methods Four hundreds cases of infantile eczema in the outpatient department of our hospital from March 2012 to January 2015 were collected and divided into observation group (220 cases) and control group (180 cases).The observation group received topical corticosteroids combined with fusidic acid cream,while the control group was treated only by topical corticosteroid.The medication time reaching to clinical cure,effect maintenance time during 30 d observation period and recurrence rate were recorded in the two groups.Results During the 30 days of observation, 50 cases of infantile eczema withdrew from the study,17 cases in the observation group and 33 cases in the control group.The average medication time in the observation group was (2.2±0.9)d,which was shorter than (3.2±1.1)d in the control group.The effect maintenance time during observation period in the observation group was (11.7±5.4) d,which was longer than (7.2±4.0)d in the control group,the difference was statistically significant(P<0.05);74.0% of recurrent cases during the observation period in the observation group manifested by mild eczema,while 57.8% in the control group manifested by mild eczema and had no need to use corticosteroid,the improvement of symptoms during recurrent period for the patients in the observation group was better than that for the patients in the control group,the difference was statistically significant (P<0.05).Conclusion Topical corticosteroids combined with fusidic acid cream for treating infantile eczema can reduce the medication time,prolong the effect maintenance time,and alleviate the recurrent symptoms.关键词
婴儿湿疹/夫西地酸乳膏/糖皮质激素类Key words
infant eczema/fusidic acid cream/glucocorticoids分类
医药卫生引用本文复制引用
卢静静,郑源泉,付桂莉..外用糖皮质激素联合夫西地酸乳膏对婴儿湿疹的干预作用[J].重庆医学,2017,46(21):2921-2922,2926,3.
