重庆医学2017，Vol.46Issue(21)：2940-2942,2944,4.DOI:10.3969/j.issn.1671-8348.2017.21.018
早期康复训练对急性脑梗死偏瘫患者的治疗效果及机制探讨
Treatment effect of early rehabilitation training on acute cerebral infarction patients with hemiplegia and its mechanism
戴贤勇 1王燕 1陈玮1
作者信息
- 1. 浙江省临海市第二人民医院神经内科 317016
- 折叠
摘要
Abstract
Objective To observe the treatment effect of early rehabilitation training on acute cerebral infarction patients with hemiplegia,and to explore its possible mechanism.Methods One hundred cases of acute cerebral infarction hemiplegia in our hospital from January 2013 to June 2016 were selected and divided into the rehabilitation training group (50 cases) and control group (50 cases).The control group was given the routine medication therapy and the rehabilitation training group was given early rehabilitation training on the basis of conventional medication therapy.The functional independence assessment (FIM),Fugl-Meyer assessment (FMA) and modified Barthel index (MBI) were used to evaluate the therapeutic effect of early rehabilitation training.The level of stromal cell-derived factor-1α (SDF-1α) in peripheral blood was measured by enzyme linked immunosorbent assay,and the level of CD34+KDR+ in peripheral blood was measured by flow cytometry.Results There was no statistically significant difference in the FIM total score,FIM sports function score,FMA score,MBI score,SDF-1α and CD34+KDR+ levels before treatment between the rehabilitation training group and the control group (P>0.05).After treatment,the FIM total score,FIM sports function score,FMA score,MBI score and SDF-1α and CD34+KDR+ levels of the rehabilitation training group were higher than those of the control group,the differences were statistically significant (P<0.05).Conclusion The effect of early rehabilitation training on acute cerebral infarction patients with hemiplegic is remarkable.The mechanism may be related to promoting the expression of SDF-1α and CD34+KDR+ in peripheral blood.关键词
脑梗死/偏瘫/早期康复训练/基质细胞衍生因子-1αKey words
brain infarction/hemiplegia/early rehabilitation training/stromal cell-derived factor-1α分类
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戴贤勇,王燕,陈玮..早期康复训练对急性脑梗死偏瘫患者的治疗效果及机制探讨[J].重庆医学,2017,46(21):2940-2942,2944,4.
