分析测试学报2017，Vol.36Issue(1)：136-144,9.DOI:10.3969/j.issn.1004-4957.2017.01.024
组合肽配体库技术富集蛋白研究进展
Progress in Research of Combinatorial Peptide Ligand Libraries for Protein Enrichment
摘要
Abstract
The low-abundance proteins play an important role in the biological activity of living organisms,involving in many physiological or pathological processes,such as metabolism,transcription and translation.Therefore,the analysis and identification of low-abundance proteins are vital in the study of proteomics.Combinatorial peptide ligand library (CPLL) is an effective method for the enrichment of low-abundance proteins,and the detection and identification of low-abundance proteins could be achieved after treated by CPLL.According to studies on the CPLL reported in recent years,its applications in different fields including the studies on low-abundance proteins in human,animal and plant protein samples were reviewed.The main purpose of this review is to provide a reference for future researches and applications of CPLL.关键词
低丰度蛋白/组合肽配体库技术/蛋白质组学/研究进展/综述Key words
low-abundance proteins/combinatorial peptide ligand library/proteomics/research progress/review分类
化学化工引用本文复制引用
樊娇娇,李苏颖,李春红,陈华,夏之宁,杨丰庆..组合肽配体库技术富集蛋白研究进展[J].分析测试学报,2017,36(1):136-144,9.基金项目
国家自然科学基金项目(81202886,21275169) （81202886,21275169）
