摘要
Abstract
Objective To investigate the high risk factors of group B streptococcus (GBS) infection in women during pregnancy and to analyze its influence on neonatal prognosis.Methods Ninety-three cases of pregnant women with positive GBS screening in pregnancy checkup and undergoing childbirth in Dongguan Maternal and Child Health Care Hospital from January 2014 to December 2015 were assigned to infection group,and 78 cases of pregnant women with negative GBS screening in checkup implemented in same hospital at same period as control group.Clinical data of pregnant women in two groups such as maternal age,degree of education,whether or not suffering from vaginitis or diabetes were compared.High risk factors of GBS infection during pregnancy were analyzed and maternal and neonatal outcomes in two groups were compared.Results Single factor analysis showed that factors including age,education level,history of abortion,pre-pregnancy checkup,home address and vaginitis were possibly associated with pregnancy GBS infection (x2 value was 5.942、11.727、4.168、14.380、4.203、8.129,respectively,all P ＜ 0.05).Multi-factor analysis showed that pre-pregnancy checkup was protective factor for GBS infection during pregnancy (OR =0.337,P ＜ 0.05),and older age,history of abortion and vaginitis were risk factors for GBS infection during pregnancy (OR value was 1.618,1.955 and 1.217,respectively,all P ＜ 0.05).Incidences of puerperal infection,premature rupture of fetal membrane and premature delivery of pregnant women in the infection group were significantly higher than those in the control group (x2 value was 4.357 and 4.318,respectively,both P ＜ 0.05).Incidences of fetal distress,neonatal asphyxia,neonatal pneumonia and neonatal jaundice in the infection group were significantly higher that those in the control group (x2 value was 4.559 and 4.207,respectively,both P ＜ 0.05).Conclusion Infection of GBS during pregnancy may increase the incidence of adverse prognosis in neonates.High risk factors of GBS infection during pregnancy include maternal age,vaginitis and abortion history.Corresponding intervention measures should be made according to risk factors to improve neonatal prognosis.关键词
妊娠期B族链球菌感染/危险因素/新生儿/预后Key words
group 13 streptococcus infection during pregnancy/risk factor/neonates/prognosis分类
医药卫生
