中国妇幼健康研究2017，Vol.28Issue(7)：802-805,4.DOI:10.3969/j.issn.1673-5293.2017.07.016
河南育龄妇女孕前血清叶酸水平及影响因素研究
Serum folic acid level and its influencing factors in women of childbearing age before pregnancy in Henan Province
摘要
Abstract
Objective To investigate the serum folic acid levels of women of childbearing age before pregnancy in Henan Province and to analyze the influencing factors to provide basis for development of health care service for folic acid intake.Methods A total of 959 women of childbearing age selected by cluster sampling in Henan Province were investigated.Serum folic acid value was determined by Beckmann micro particle chemiluminescence method.The levels of serum folic acid in different subgroups were compared by chi-square test and variance analysis.Univariate Logistic regression was used to analyze the factors affecting serum folic acid level, and statistically significant variables were analyzed by multivariate analysis.Results The average level of serum folic acid in women of childbearing age was 10.36±6.14ng/mL.Folic acid level of childbearing age women of older age, with higher education, having occupation of teachers or civil servants, with higher frequency of pregnancy was higher (χ2 value was 12.51, 14.63, 27.05 and 71.96, respectively, all P<0.05).Univariate analysis showed that age, education level, occupation, BMI, number of pregnancy, economic stress and vitamin supplementation were related to folic acid levels in women of childbearing age.Multivariate analysis showed that compared with normal population, obese women and those with moderate to severe economic stress had a higher risk of lower folic acid level (OR=2.51,95%CI:1.28-4.920;OR=2.30,95%CI:1.10-4.80).Compared to women with college and above education, women with education of junior high school and below and high school had a higher risk of lower folic acid level (OR=1.83,95%CI:1.14-2.92;OR=1.64,95%CI:1.03-2.61).Vitamin supplementation for more than one month could significantly reduce the risk of lower folic acid level (OR=0.18,95%CI:0.04-0.77).Conclusion Folic acid supplement program and nutrition and health education should be presented to women of lower age, peasant occupation, obesity and those under greater economic pressure.关键词
叶酸/育龄妇女/肥胖/血清Key words
folic acid/women of childbearing age/obesity/serum分类
医药卫生引用本文复制引用
郭桐君,王媛媛,蒋丽芳,张亚,扬永俊,张倩,曹丽幸,刘笃佳,唐文斌,马楚洋..河南育龄妇女孕前血清叶酸水平及影响因素研究[J].中国妇幼健康研究,2017,28(7):802-805,4.基金项目
国家重点研发计划资助项目(2016YFC1000307) （2016YFC1000307）
