解放军医药杂志2017，Vol.29Issue(6)：96-98,3.DOI:10.3969/j.issn.2095-140X.2017.06.027
脓毒症患者血清降钙素原、C-反应蛋白水平及诊断意义
Serum Procalcitonin and C-Reactive Protein Levels in Patients with Sepsis and Their Diagnostic Significances
摘要
Abstract
Objective To investigate serum procalcitonin (PCT) and C-reactive protein (CRP) in patients with acute sepsis and their diagnostic significances.Methods A total of 60 patients with acute sepsis admitted during December 2014 and September 2015 were divided into mild sepsis group (n =40) and severe sepsis group (n =20) according to patient's condition,and another 30 healthy people taking medical examinations at the same period were selected as normal healthy group.Serum PCT and CRP levels were detected in three groups to analyze their significances of PCT and CRP for clinical significances of patients with acute sepsis.Results Serum PCT,CRP and lactic acid levels in severe sepsis group were significantly higher than those in mild sepsis and normal healthy groups (P ＜ 0.05),and the levels in mild sepsis group were significantly higher than those in normal healthy group (P ＜ 0.05).Serum CRP and PCT levels were positively correlated with serum lactate levels (P ＜ 0.001).CRP and PCT levels also showed a linear positive correlation (P ＜ 0.001).Conclusion Serum PCT and CRP levels can be used as indexes in early diagnosis of sepsis,accurately assess severity,guide clinicians and establish rational treatment plan for patients with sepsis.关键词
脓毒症/降钙素原/C-反应蛋白/乳酸Key words
Sepsis/Procalcitonin/C-reactive protein/Lactic acid分类
医药卫生引用本文复制引用
柴林,肖敏,杨贤义,郭辉..脓毒症患者血清降钙素原、C-反应蛋白水平及诊断意义[J].解放军医药杂志,2017,29(6):96-98,3.基金项目
湖北省教育厅重点项目(D20122402) （D20122402）
