解放军医药杂志2017，Vol.29Issue(6)：107-109,3.DOI:10.3969/j.issn.2095-140X.2017.06.030
帕罗西汀联合心理干预治疗产后抑郁的临床观察
Clinical Observation of Paroxetine Combined with Mental Intervention in Treatment of Postpartum Depression
杜玉青 1侯红娟2
作者信息
- 1. 050000石家庄,河北友爱医院精神卫生科
- 2. 073000河北定州,定州市中医医院妇产科
- 折叠
摘要
Abstract
Objective To observe clinical effect of Paroxetine combined with mental intervention in treatment of postpartum depression.Methods A total of 200 patients with postpartum depression during September 2016 and March 2017 were divided into observation group and control group (n =100 for each group) according to treatment methods.All patients received mental intervention,and the observation group was added with Paroxetine.Clinical effect was evaluated in each group.In two groups,5-hydroxytryptamine (5-HT) and serum homocysteine (Hcy) levels were respectively detected before treatment and after treatment for 6 weeks,and incidence of drug adverse reaction was observed.Results The total effective rate in observation group was significantly higher than that in control group (P ＜ 0.05).After treatment,Hamilton anxiety and Hamilton rating scale for depression scores were significantly lower than those before treatment in two groups (P ＜ 0.05),and the scores in observation group were significantly lower than those in control group (P ＜ 0.05).After treatment,5-HT level in observation group was significantly higher (P ＜ 0.05),while HCY level was significantly lower than those before treatment in same group and in control group (P ＜ 0.05).Conclusion Aroxetine combined with mental intervention in treatment of postpartum depression is effective.关键词
帕罗西汀/抑郁症,产后/心理疗法Key words
Paroxetine/Depression, postpartum/Psychotherapy分类
医药卫生引用本文复制引用
杜玉青,侯红娟..帕罗西汀联合心理干预治疗产后抑郁的临床观察[J].解放军医药杂志,2017,29(6):107-109,3.
