中国实用神经疾病杂志2017，Vol.20Issue(13)：47-49,3.
血管性痴呆患者神经肽Y和降钙素基因相关肽的临床意义
Changes of serum neuropeptide Y and calcitionin gene related peptide in patients with vascular dementia and its clinical significance
卢燕婉 1常立军 1吕海东1
作者信息
- 1. 焦作市人民医院神经内科,河南 焦作 454002
- 折叠
摘要
Abstract
Objective To investigate the clinical significance and the the serum levels of neuropeptide Y and calcitionin gene related peptide in the patients with vascular dementia.Methods The serum levels of NPY and CGRP were detemined by Radiation immunity analysis,in 66 cases of VD patients and 59 cases of patients with cerebral infarction but no dementia and 40 cases of healthy.The relation of the levels of NPY and CGRP was explored.Results The serum levels of NPY in the VD group and the CI group were significantly higher than the normal people(P<0.01).The serum levels of NPY in VD group were higher than CI group(P<0.05).The serum levels of CGRP in VD group and CI group were significantly higher than normal people(P<0.01).The serum levels of CGRP in VD group were significantly higher than CI group(P<0.01).There was negative correlation between the serum levels of NPY and CGRP(P<0.05).Conclusion NPY is higher and CGRP is lower in VD group.There is negative correlation between the serum levels of NPY and CGRP.The disorder of the diastolic function of cerebrovascular could be the result of ischemia,and may lead to brain damage.Long-term chronic ischemic and hypoxia of brain is possibly one of pathogenesies of vascular dementia.关键词
血管性痴呆/神经肽Y/降钙素基因相关肽Key words
Vascular dementia/Neuropeptide Y/Calcitionin gene related peptide分类
医药卫生引用本文复制引用
卢燕婉,常立军,吕海东..血管性痴呆患者神经肽Y和降钙素基因相关肽的临床意义[J].中国实用神经疾病杂志,2017,20(13):47-49,3.
