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抗衰老机制研究进展

莫睿 魏智民 杨云生

解放军医学杂志2017,Vol.42Issue(8):743-748,6.
解放军医学杂志2017,Vol.42Issue(8):743-748,6.DOI:10.11855/j.issn.0577-7402.2017.08.16

抗衰老机制研究进展

Advances in research of anti-aging mechanism

莫睿 1魏智民 2杨云生3

作者信息

  • 1. 100853 北京 解放军总医院消化病中心
  • 2. 300071 天津 南开大学医学院
  • 3. 100853 北京 解放军医学院
  • 折叠

摘要

Abstract

Aging is a biological process and state characterized by morphological change, hypofunction and metabolic disorder, often accompanied by severe degenerative diseases, including amyotrophy, atherosclerosis, neurodegeneration, and so on. Age-related diseases not only decrease the life quality of the elderly, but also impose great burden on family and society. As population aging, we are increasingly coming to realize that the longevity we want should be healthy aging but not simple increase of lifespan. By researching on the yeast, C. elegans, drosophila, mice and humans, we get to know the mechanisms of aging and methods for anti-aging, such as dietary restriction and use of anti-aging drugs like rapamycin. In this review, we summarized mainly the studies on mechanisms of aging and elaborate associated anti-aging strategies and underlying mechanisms.

关键词

衰老/饮食/抗衰老药物

Key words

aging/diet/anti-aging drugs

分类

医药卫生

引用本文复制引用

莫睿,魏智民,杨云生..抗衰老机制研究进展[J].解放军医学杂志,2017,42(8):743-748,6.

解放军医学杂志

OA北大核心CSCDCSTPCD

0577-7402

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