检验医学与临床2017，Vol.14Issue(12)：1706-1708,3.DOI:10.3969/j.issn.1672-9455.2017.12.009
血栓弹力图在指导阿司匹林相关性脑出血治疗中的应用
Application of thromboelastography in guiding therapy of aspirin related intracerebral hemorrhage
摘要
Abstract
Objective To evaluate the clinical guiding effect of thromboelastography in treating the patients with aspirin related intracerebral hemorrhage(ICH).Methods The clinical data in 45 ICH in patients with taking aspirin and 45 ICH in patients without taking aspirin in our hospital from January 2015 to December 2016 were analyzed retrospectively.All patients with aspirin were detected by thrombelastography on admission.Among them,the patients with AA inhibition rate ≥50 ％ were infused by platelet.Then thrombelastography was performed again.After the TEG-MAX(AA) and AA inhibition rate were normal,the therapy was conducted again.The two groups adopted the corresponding therapy according to the disease condition.The mortality rate at 1,3 months was observed in the two groups.The neural function impairment was evaluated by adopting GOS score and Barthel indexe (BI) in the two groups.Results The AA inhibition rate in 38 cases of the aspirin group was ＞50％,after infusing platelet,TEG-MAX(AA) was extended,the AA inhibition rate was decreased,showing statistical difference compared with before treatment(P＜0.05).The mortality rate after 1-month treatment in the aspirin group was higher than that in the non-aspirin group without statistical difference(P＞0.05);the GOS score and BI in the aspirin group were lower than those in the non-aspirin group,the difference was statistically significant(P＜0.05).Conclusion The ICH patients with aspirin have poor coagulation function and higher mortality rate.Thrombelastograrhy has a certain effect for guiding treatment in ICH patients with aspirin.关键词
血栓弹力图/血小板抑制率/阿司匹林/脑出血Key words
thrombelastograrhy/platele inhibition ratio/aspirin/intracerebral hemorrhage引用本文复制引用
宋会双,姚文娟,刘炜,安艳春,张换立,黄万刚,朱海伟,李静..血栓弹力图在指导阿司匹林相关性脑出血治疗中的应用[J].检验医学与临床,2017,14(12):1706-1708,3.基金项目
2015年河北省廊坊市科技支撑计划项目(2015013031). （2015013031）
