检验医学与临床2017，Vol.14Issue(12)：1709-1711,3.DOI:10.3969/j.issn.1672-9455.2017.12.010
丙泊酚与七氟醚麻醉对小儿腹腔镜疝囊高位结扎术血流动力学及并发症的影响
Effects of propofol and sevoflurane anesthesia on hemodynamics and complications in pediatric laparoscopic hernia sac high ligation
摘要
Abstract
Objective To investigate the effects of propofol and sevoflurane anesthesia on hemodynamics and complications in pediatric laparoscopic hernia sac high ligation.Methods Eighty-four children cases of laparoscopic hernia sac high ligation from January 2014 to January 2015 were selected as the research subjects and divided into the propofol group(n=42) and sevoflurane group (n=42) according to the random number table method.Two groups were injected by 1.5 mg/kg ketamine for conducting anesthetic induction after entering the operation room.The propofol group was intraoperatively and intravenously infused with 8-10 mg/(kg · h) propofol for maintenance anesthesia,while the sevoflurane group was introperatively performed the mask inhalation of 2.5％-3.5％ sevoflurane for maintenance anesthesia.The mean arterial pressure (MAP),heart rate (HR),oxygen saturation (SPO2),respiration end carbon dioxide (PET CO2) at preoperative 5 min (T0),pneumoperitoneum establishment (T1),5 min after pneumoperitoneum establishment(pneumoperitoneum establishment),deflation at the operation end(T3) and 5 min after deflation (T4) were recorded in the two groups.The ketamine dosage,anesthesia time,recovery time,extubation time and anesthesia-related complications were observed in the two groups.Results The levels of MAP,HR and PET CO2 at T1-T3 in the two groups were significantly higher than those at T0,which at T4 recovered to the preoperative levels.The levels of MAP,HR,SPO2 and PEr CO2 at T1-T3 in the sevoflurane group were significantly lower than those in the propofol group,the difference was statistically significant (P＜0.05).The ketamine amount in the sevoflurane group was less than that in the propofol group(P＜0.05),the anesthesia time,recovery time and extubation time were shorter than those in the propofol group(P＜0.05).The occurrence rates of nausea,vomiting,restlessness and respiratory depression in the sevoflurane group were significantly lower than those in the propofol group,the difference was statistically significant (P＜0.05).Conclusion Sevoflurane general anesthesia used in pediatric laparoscopic hernia sac high ligation can effectively stabilize the hemodynamic indicators with rapid postoperative recovery,safety and reliability.关键词
丙泊酚/七氟醚/疝囊结扎/血流动力学Key words
propofol/sevoflurane anesthesia/hernia sac ligation/hemodynamics引用本文复制引用
史宇平,田园,杨海昌,李建..丙泊酚与七氟醚麻醉对小儿腹腔镜疝囊高位结扎术血流动力学及并发症的影响[J].检验医学与临床,2017,14(12):1709-1711,3.基金项目
河北省科学技术厅科技项目(20143453). （20143453）
