检验医学与临床2017，Vol.14Issue(12)：1726-1728,1731,4.DOI:10.3969/j.issn.1672-9455.2017.12.016
528例登革热患者临床表现与实验室数据的回顾性分析
Retrospective analysis of clinical manifestations and laboratory data in 528 dengue cases
摘要
Abstract
Objective To analyze the changes of clinical manifestations and laboratory indexes in the patients with dengue fever (DF).Methods The symptoms,signs and laboratory data among 528 dengue cases in our hospital during 2015 dengue outbreak of Chaozhou were retrospectively analyzed,moreover which were compared with the general population,meanwhile whether the differences of various indexes were existed among ordinary DF,dengue hemorrhagic fever(DHF) and severe DF.Results All cases were infected by dengue virus type Ⅱ (DENV-2).The major clinical manifestations were fever,headache,rash,muscular soreness,ecchymosis,bleeding,vomiting and diarrhea.Compared with the general population with no dengue fever infection,the following laboratory indexes showed significant differences in the dengue fever group,including WBC,HCT,PLT,ALT,AST,TG,TCHO,HDLC and LDLC(P=0.000).Four hundreds and ninety-one cases(93.0％) were ordinary DF,22 cases(4.2％) were DHF and 15 cases (2.8％) were severe DF.The levels of WBC,PLT,ALT,AST,CK,CK-MB and LDH had statistically significant differences between the severe DF group and ordinary DF group(P＜0.05).In addition,there were statistical differences inWBC,ALT,AST,CK,CK-MB and LDH between severe DF group and DHF group(P＜0.05).Conclusion Many laboratory indexes show different degrees of abnormality in the patients with DF.The comprehensive analysis of these data could assist and guide the clinical diagnosis and treatment,which has an important significance for the control of DF infection.关键词
登革热/临床表现/实验室数据Key words
dengue fever/clinical manifestation/laboratory data引用本文复制引用
林芬,杨辉,杨立业,林树强,陈建永,李贵才,林华容,蔡文,王朋朋..528例登革热患者临床表现与实验室数据的回顾性分析[J].检验医学与临床,2017,14(12):1726-1728,1731,4.基金项目
2013年“杨帆计划”培养高层次人才项目资助. （）
