检验医学与临床2017，Vol.14Issue(12)：1759-1761,3.DOI:10.3969/j.issn.1672-9455.2017.12.028
黄芪桃红汤辅助化疗对宫颈癌患者细胞免疫功能的影响
Effect of Huangqi Taohong Decoction adjuvant chemotherapy on cellular immune function in patients with cervical cancer
王治荣 1公丕军 2王桂贤 2赵宗霞3
作者信息
- 1. 西北工业大学医院妇产科,西安710072
- 2. 西安交通大学第二附属医院妇产科,西安710004
- 3. 西安医学院第二附属医院妇产科,西安710038
- 折叠
摘要
Abstract
Objective To explore the effect of Huangqi Taohong Decoction adjuvant chemotherapy on the cellular immune function in the patients with cervical cancer.Methods Seventy-two patients with cervical cancer admitted in the Second Affiliated Hospital of Xi'an Jiantong University from June 2013 to June 2016 were selected and divided into the control group and experimental group according to the random sampling method,36 cases in each group.The control group adopted the radiochemotherapy,while on this basis the experimental group was added with Huangqi Taohong Decoction.The two groups were treated for 3 courses (4 weeks as a treatment course).The changes of immune function and clinical effect before and after treatment were compared between the control group and experimental group.Results After 3 courses of treatment,the CD8+ value of the experimental group was significantly decreased compared with that before treatment,which was better than that in the control group,the CD3+,CD4+,NK cells and CD4 +/CD8 + values in the experimental group were significantly increased (P＜ 0.05);the CD4 +/CD8 + value and CD8 + value after treatment in the control group were slightly increased compared with before treatment,other indexes were decreased,the differences were not statistically s ignificant(P＞0.05).The total effective rate was 80.5 ％ in the experimental group and 61.1％ in the control group,the total effective rate in the experimental group was significantly higher than that in the control group with statistical difference(P＜0.05).The adverse reaction rate was 24.6％ in the experimental group,which was lower than 42.6％ in the control group,the difference was statistically significant(P＜0.05).The KPS score of the experimental group was higher than that of the control group,and the quality of life in the experimental group was higher than that in the control group(P＜0.05).Conclusion Apllying Huangqi Taohong Decoction adjuvant chemotherapy can significantly increase the immune function in the patients with cervical,improves the clinical treatment effect and is worthy of clinical promotion and application.关键词
黄芪桃红汤/宫颈癌/免疫功能/生存质量Key words
Huangqi Taohong Decoction/cervical cancer/immune function/survival quality引用本文复制引用
王治荣,公丕军,王桂贤,赵宗霞..黄芪桃红汤辅助化疗对宫颈癌患者细胞免疫功能的影响[J].检验医学与临床,2017,14(12):1759-1761,3.
