山东医药2017,Vol.57Issue(22):19-22,4.DOI:10.3969/j.issn.1002-266X.2017.22.006
维持性腹膜透析患者肺淤血与生活质量的关系
Relationship between pulmonary congestion and quality of life in maintenance peritoneal dialysis patients
摘要
Abstract
Objective To observe the pulmonary congestion (PC) and quality of life (QOL) in maintenance peritoneal dialysis (MPD) patients and to investigate the relationship between them.Methods We collected the clinical data of 105 MPD patients,evaluated PC with B-line number on pulmonary ultrasonography,evaluated QOL by concise health questionnaire (SF-36),and calculated the physical health score (PCS) and mental health score (MCS).The association between B line number and PCS,MCS was examined by Spearman correlation analysis.Patients were respectively divided into two groups according to the median of PCS and MCS.Demographic data and clinical parameters were compared between the two groups,and then multivariate binary logistic regression analysis was applied to determine the independent risk factors for QOL.Results A total of 105 MPD patients were included.Median B line number was 4 (0,17).PC was detected in 52 cases,PCS was 52.8 (44.8,59.8) points,and MCS was 54.5 (46.8,60.8) points.B line number was negatively correlated with PCS and MCS (r =-0.589,-0.464,both P < 0.01).Compared with patients with high PCS,B lines number,serum B-type natriuretic peptide,average age,proportion of diabetic kidney disease and proportion of previous cardiocerebrovascular events were higher (P < 0.05),while hemoglobin and serum albumin were lower in patients with low PCS (both P < 0.01).Compared with patients with high MCS,B line number and serum B-type natriuretic peptide were higher (both P <0.01),but hemoglobin and serum albumin were lower in patients with low MCS (both P <0.01).Multivariate analysis showed that B line number,hemoglobin,age,and previous cardiocerebrovascular events were independent risk factors for PCS (all P < 0.01),however,only B line number and hemoglobin were independent risk factors for MCS (both P < 0.05).Conclusion MPD patients have high prevalence of PC and low level of QOL,and PC may be an important reason for the decline of QOL in these patients.关键词
腹膜透析/肺淤血/生活质量/肺超声/慢性肾功能衰竭Key words
peritoneal dialysis/pulmonary congestion/quality of life/lung ultrasonography/chronic renal failure分类
医药卫生引用本文复制引用
王加伟,卢来顺,洪春燕,王良玉,唐小玲..维持性腹膜透析患者肺淤血与生活质量的关系[J].山东医药,2017,57(22):19-22,4.基金项目
广东省医学科研基金项目(B2016115). (B2016115)