世界中医药2017，Vol.12Issue(6)：1235-1243,1247,10.DOI:10.3969/j.issn.1673-7202.2017.06.007
中医非药物治疗老年性痴呆的证据总结与评价
Summary and Evaluation of Evidences of Non-pharmacological Intervention of Traditional Chinese Medicine in Alzheimer's Disease
摘要
Abstract
Objective:To summarize and evaluate the evidence of non-pharmacological intervention of Traditional Chinese Medical in Alzheimer's disease (AD) and provide supports.Methods:A systematic literature search was performed.CNKI,Wanfang,Pubmed,Medline,Cochrane library,Embase,PsycINFO,CINAHL,CQVIP,ACP Journal Club (www.acpjc.org) were searched for related systematic reviews.The methodological quality and the quality of the evidences were evaluated using the Assessment of Multiple Systematic Reviews (AMSTAR) and Grading of Recommendations Assessment,Development and Evaluation (GRADE) approaches.The guideline was evaluated using AGREE II.Results:Seven systematic reviews and meta-analyses of acupuncture for AD were included,one of aromatherapy and one of non-pharmacological intervention for AD,four of massage (included one article of acu-point massage).The compliance with AMSTAR checklist items regarding to acupuncture systematic reviews ranged from 6.5 to 11.The quality of the bodies of evidence of acupuncture we assessed ranged from very low to moderate,and no high quality bodies of evidence were found.The effectiveness of aromatherapy for agitation or behavior symptom of AD remained inconclusive.Acu-point massage revealed positive effective in controlling psychological or behavior symptoms.Conclusion:There is still expectations for more researches including primary and secondary literature about non-pharmacological intervention of TCM for AD.The overall quality of the evidence remains sub-optimal which raises concerns regarding their roles in clinical practice.Thus,the conclusions in reviews must be treated with caution and their roles in clinical practice should be limited.关键词
中医非药物/证据评价/AMSTAR工具/GRADE系统/AGREE Ⅱ工具/指南构建Key words
Non-pharmacological intervention in Traditional Chinese Medicine/Evidence evaluation/AMSTAR tool/GRADE approach/AGREE Ⅱ/Guideline development分类
医药卫生引用本文复制引用
靳英辉,魏洪悦,王云云,李紫梦,许良燕,韩蕙安,杨柳,商洪才..中医非药物治疗老年性痴呆的证据总结与评价[J].世界中医药,2017,12(6):1235-1243,1247,10.基金项目
国家自然科学基金青年项目(编号:81603496)——中西医调摄护理多源证据体构建及整合评价 （编号:81603496）
