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王氏保赤丸联合微生态及锌制剂治疗对小儿迁延性腹泻血清及结肠灌洗液相关指标的影响

李霞 吴嘉婴 周小建

世界中医药2017,Vol.12Issue(6):1350-1353,4.
世界中医药2017,Vol.12Issue(6):1350-1353,4.DOI:10.3969/j.issn.1673-7202.2017.06.034

王氏保赤丸联合微生态及锌制剂治疗对小儿迁延性腹泻血清及结肠灌洗液相关指标的影响

Effect of Wang's Baochi Pill Combined with Probiotics and Zinc Preparation on Serum and Colonic Lavage Indicators in Treating Pediatric Persistent Diarrhea

李霞 1吴嘉婴 1周小建2

作者信息

  • 1. 上海国际医学中心儿科,上海,201318
  • 2. 上海交通大学附属第一人民医院儿科,上海,200080
  • 折叠

摘要

Abstract

Objective:To study the effect of Wang's Baochi Pill combined with probiotics and zinc preparation on serum and colonic lavage indicators in treating pediatric persistent diarrhea.Methods:A total number of 106 children with persistent diarrhea in the hospital from March 2013 to April 2016 were randomly divided into control group and treatment group,with 53 cases in each group.The control group received routine treatment and probiotics and zinc preparation,while the treatment group additionally received Wang's Baochi Pill.The levels of serum and colonic lavage indicators were compared between the two groups before and after treatment,and the clinical efficacy was analyzed.Results:The levels of IL-6,IL-8,NO and MDA in serum and colonic lavage fluid after treatment were lower than those before the treatment (P < 0.05).The levels of superoxide dismutase (SOD) and serum zinc were higher than those before the treatment and the difference in the two groups was significant (P < 0.05),and the treatment group was closer to the normal compared with the control group.The total effective rate of treatment group was 86.79% which was higher than that of control group (62.26%),showing statistically significant difference between the two groups (P < 0.0l).Conclusion:Wang's Baochi Pill combined with probiotics and zinc preparation in the treatment of persistent diarrhea for children have better effect in serum and colonic lavage related indicators,which is worth of promotion.

关键词

王氏保赤丸/微生态制剂/锌制剂/小儿迁延性腹泻/血清/结肠灌洗液

Key words

Wang's Baochi Pill/probiotics/Zinc preparations/persistent diarrhea in children/Serum/Colonic lavage lotion

分类

医药卫生

引用本文复制引用

李霞,吴嘉婴,周小建..王氏保赤丸联合微生态及锌制剂治疗对小儿迁延性腹泻血清及结肠灌洗液相关指标的影响[J].世界中医药,2017,12(6):1350-1353,4.

世界中医药

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1673-7202

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