世界中医药2017，Vol.12Issue(6)：1479-1483,5.DOI:10.3969/j.issn.1673-7202.2017.06.065
不同年龄段和不同转移状态的三阴性乳腺癌患者的临床和病理特征分析
Analysis of Clinical and Pathological Characteristics of Triple Negative Breast Cancer Patients with Different Ages and Different Baseline Metastasis Status
摘要
Abstract
Objective:To analyze clinical and pathological charateristics of triple negative breast cancer (TNBC) patients with different ages and different baseline metastasis status.Methods:A retrospective cohort study was conducted,in which TNBC patients were grouped according to their ages (younger than 35 years old,35 ～ 60,older than 60) and baseline metastasis status (with or without baseline metastasis).Clinical and pathological charateristics were compared as well as the clinical symptoms of Chinese Medicine.Results:Among the 108 TNBC patients enrolled,their average age was around 47;most patients received modified radical mastectomy;major pathological type was invasive ductal carcinoma,36.1％ patients showed positive ALN,8 patients (7.4％) had metastasis after surgery.Patients younger than 35 preferred conserving surgery.Compared with patients without baseline metastasis,patients with baseline metastasis received more surgeries,with higher pathological stages,and later receipt of TCM treatment.There was no significant difference of TCM symptoms among the patients with different ages.Patients with baseline metastasis showed higher rate of anorexia and gastrointestinal symptoms,such as nausea and vomit.Conclusion:There were significant differences of clinical characteristics among TNBC patients with different ages and baseline metastasis status,but no differences on clinical symptoms of TCM.The impact of these clinical differences on long term outcomes needs further follow-up.关键词
乳腺癌/三阴性乳腺癌/临床特征/年龄/转移/中医治疗Key words
Breast cancer/Triple negative breast cancer/Clinical characteristic/Age/Metastasis/Chiense Medicine treatment分类
医药卫生引用本文复制引用
刘静,陆德铭..不同年龄段和不同转移状态的三阴性乳腺癌患者的临床和病理特征分析[J].世界中医药,2017,12(6):1479-1483,5.基金项目
第五批全国老中医药专家学术经验继承班课题,上海市卫生和计划生育委员会中医药继承专项研究课题(编号:2014S25) （编号:2014S25）
