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线粒体钙蛋白酶系统

常泓 尹淑琴 袁建琴

山西农业大学学报(自然科学版)2017,Vol.37Issue(7):469-476,8.
山西农业大学学报(自然科学版)2017,Vol.37Issue(7):469-476,8.

线粒体钙蛋白酶系统

Mitochondrial calpain system

常泓 1尹淑琴 2袁建琴2

作者信息

  • 1. 山西农业大学期刊社,山西太谷030801
  • 2. 山西农业大学生命科学学院,山西太谷030801
  • 折叠

摘要

Abstract

[Objective]The aim of this article was to overview the members,functions and regulations of calpains in mitochondrial.[Method] Literature review method.[Results]Calpain have previously been considered as the cytoplasmic enzymes,research in the recent past demonstrated that CAPN1,CAPN2 and CAPN10 are present in mitochondria,which play important roles in a variety of pathophysiological conditions including necrotic and apoptotic cell death phenomena,[Conclusion]This review outlined the key features of the mitochondrial calpain system,and its roles in several cellular and biochemical events under normal and some pathophysiological conditions.

关键词

线粒体/CAPN1/CAPN2/CAPN10/钙蛋白酶抑制蛋白/细胞凋亡

Key words

Mitochondria/CAPN1/CAPN2/CAPN10/Calpastatin/Apoptosis

分类

生物科学

引用本文复制引用

常泓,尹淑琴,袁建琴..线粒体钙蛋白酶系统[J].山西农业大学学报(自然科学版),2017,37(7):469-476,8.

基金项目

国家自然科学基金(30271003) (30271003)

山西省科技攻关项目(20090311037) (20090311037)

山西省青年基金项目(20021038) (20021038)

山西农业大学学报(自然科学版)

OA北大核心CSTPCD

1671-8151

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