山西农业大学学报(自然科学版)2017,Vol.37Issue(7):469-476,8.
线粒体钙蛋白酶系统
Mitochondrial calpain system
摘要
Abstract
[Objective]The aim of this article was to overview the members,functions and regulations of calpains in mitochondrial.[Method] Literature review method.[Results]Calpain have previously been considered as the cytoplasmic enzymes,research in the recent past demonstrated that CAPN1,CAPN2 and CAPN10 are present in mitochondria,which play important roles in a variety of pathophysiological conditions including necrotic and apoptotic cell death phenomena,[Conclusion]This review outlined the key features of the mitochondrial calpain system,and its roles in several cellular and biochemical events under normal and some pathophysiological conditions.关键词
线粒体/CAPN1/CAPN2/CAPN10/钙蛋白酶抑制蛋白/细胞凋亡Key words
Mitochondria/CAPN1/CAPN2/CAPN10/Calpastatin/Apoptosis分类
生物科学引用本文复制引用
常泓,尹淑琴,袁建琴..线粒体钙蛋白酶系统[J].山西农业大学学报(自然科学版),2017,37(7):469-476,8.基金项目
国家自然科学基金(30271003) (30271003)
山西省科技攻关项目(20090311037) (20090311037)
山西省青年基金项目(20021038) (20021038)