中国全科医学2017，Vol.20Issue(24)：3004-3007,3014,5.DOI:10.3969/j.issn.1007-9572.2017.24.013
1996-2015年北京积水潭医院住院肺血栓栓塞症患者临床流行病学特征及诊治变迁情况
Clinical Epidemiological Characteristics and Changes of Diagnosis and Treatment in Hospitalized Patients with Pulmonary Thromboembolism in Beijing Jishuitan Hospital from 1996 to 2015
摘要
Abstract
Objective To understand the clinical epidemiological characteristics and changes of diagnosis and treatment of pulmonary thromboembolism (PTE)in hospitalized patients in Beijing Jishuitan Hospital,and to help the prevention and treatment of PTE in the future.Methods From August to October in 2016,the clinical data of 267 hospitalized patients with PTE confirmed in Beijing Jishuitan Hospital from 1996 to 2015 were collected.The incidence and prognosis,demographic characteristics,clinical data(including the source of the department and the occurrence of complications),diagnosis and treatment of PTE patients from 1996 to 2015 were analyzed. Results A total of 48 PTE patients were diagnosed in 1996-2005.A total of 219 PTE patients were diagnosed in 2006-2015,which was an increase of 3.6 times of that in 1996-2005.The average annual incidence of PTE in patients was 3.32/million in 1996-2005.The average annual incidence of PTE in patients was 6.28/million in 2006-2015,which was 1.9 times of that in 1996-2005.The mortality rate in 2006-2010 and in 2011-2015 were all lower than that in 1996-2000 and in 2001-2005 period(P<0.05).Among the 267 PTE patients,144 were male,123 were female,the male-female ratio was 1.17∶1.00.And the age of these patients ranged from 18 to 96 years.Female PTE patients aged 21-40 years old were significantly less than male(P<0.05),but female PTE patients aged 61-80 years old were significantly more than male(P<0.05).The most common sources of department of the 267 PTE patients were the department of orthopedics(39.7%),respiratory medicine(31.5%),cardiology(9.4%)and vascular surgery(4.9%).The most common complications of the 267 PTE patients were hypertension(44.9%),chronic heart and lung disease(33.0%,including chronic obstructive pulmonary disease,coronary heart disease,pulmonary heart disease,chronic cardiac dysfunction,etc),trauma and fracture(30.0%),diabetes and thyroid disease(22.8%) and malignant tumor(16.5%).The PTE patients diagnosed by clinical accounted for 60.0% in 1996-2000.The PTE patients diagnosed by CT pulmonary angiography(CTPA) in 2006-2010 and in 2011-2015 accounted for 66.2% and 62%,respectively.The PTE patients diagnosed by CTPA,pulmonary radionuclide ventilation/perfusion(V/Q) and pulmonary angiography(PAA) totally accounted for 73.2% in 2011-2015.The diagnosis methods of PTE in 1996-2000 was significantly different from that in 2006-2010,2011-2015(P<0.05).The diagnosis methods of PTE in 2001-2005 was significantly different from that in 2006-2010,2011-2015(P<0.05).The treatment methods of PTE in 2006-2010 was significantly different from that in 2001-2005,2006-2010,2011-2015(P<0.05).Conclusion The number of hospitalized PTE patients in Beijing Jishuitan Hospital increases year by year from 1996 to 2015.The peak age of onset of PTE in female is later than that of male.The diagnosis pattern has changed from clinical diagnosis to diagnosis combined with CTPA and other objective examinations.The standardized diagnosis and treatment can significantly reduce PTE mortality.关键词
肺栓塞/流行病学研究/诊断/治疗Key words
Pulmonary embolism/Epidemiologic studies/Diagnosis/Therapy分类
医药卫生引用本文复制引用
王晓芳,李笠,张运剑..1996-2015年北京积水潭医院住院肺血栓栓塞症患者临床流行病学特征及诊治变迁情况[J].中国全科医学,2017,20(24):3004-3007,3014,5.基金项目
北京市科学技术委员会资助课题(Z141107002514153) （Z141107002514153）
