中国全科医学2017，Vol.20Issue(24)：3043-3046,4.DOI:10.3969/j.issn.1007-9572.2017.06.y52
穿刺活检未证实为前列腺癌的血清前列腺特异性抗原阳性的原发部位不明的肿瘤一例报道并文献复习
Carcinoma of Unknown Primary Origin with Markedly Elevated PSA Levels Unconfirmed by Repeat Prostate Biopsy:a Case Report and Review of the Literature
廖义翔 1周家杰 1刘涛 1曾金敏 1杨光华1
作者信息
- 1. 434020湖北省荆州市,荆州市中心医院 长江大学第二临床医学院 华中科技大学同济医学院附属荆州医院泌尿外科
- 折叠
摘要
Abstract
Objective To improve the awareness level of the cancer of unknown primary origin (CUP) with markedly elevated PSA levels unconfirmed by repeat prostate biopsy.Methods We reported the diagnosis and treatment of one case of CUP with markedly elevated PSA levels but was not confirmed by repeat prostate biopsy form Jingzhou Central Hospital,and reviewed the corresponding literature.We searched and included 8 articles in which totaled 9 such patients were reported from Wanfang data and PubMed as of 2016-10-09.We analyzed and summarized the clinical data of the above 9 cases and one case received by Jingzhou Central Hospital.Results The data of the 10 cases:male aged 61-80;negative results of digital rectal examination (the prostate was soft,medium-sized without obvious nodules );serum PSA levels were 56.3-4 222.0 μg/L;bone metastases or pelvic lymph node metastases were found;negative results of repeat prostate biopsy;diagnostic result was CUP with markedly elevated PSA levels;therapeutic regimen was palliative endocrine therapy.Conclusion For patients with CUP,markedly elevated PSA levels and negative results of repeat prostate biopsy,palliative endocrine therapy is suggested to use in order to delay the progress of the disease or relieve the symptoms and improve the quality of life.关键词
前列腺肿瘤/活组织检查,针吸/前列腺特异抗原/肿瘤,未知原发灶Key words
Prostatic neoplasms/Biopsy/aspiration/Prostate-specific antigen/Neoplasms/unknown primary origin分类
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廖义翔,周家杰,刘涛,曾金敏,杨光华..穿刺活检未证实为前列腺癌的血清前列腺特异性抗原阳性的原发部位不明的肿瘤一例报道并文献复习[J].中国全科医学,2017,20(24):3043-3046,4.
