中国全科医学2017，Vol.20Issue(24)：3051-3055,5.DOI:10.3969/j.issn.1007-9572.2017.04.y11
微生物-肠-脑轴与帕金森病研究进展
Recent Developments in Microbiota-gut-brain Axis and Parkinson′s Disease
关小雪 1承欧梅 1王雨婵1
作者信息
- 1. 400010 重庆市,重庆医科大学附属第一医院神经内科
- 折叠
摘要
Abstract
Parkinson′s disease(PD) is a common neurodegenerative disorder.There have been studies suggesting that the gut microbiota may have a prominent role in modulating the bidirectional interaction between brain and gut,therefore proposing the microbiota-gut-brain axis,which also exists in PD.Disregulation of the microbiota-gut-brain axis is closely associated with the gastrointestinal dysfunction in PD.Moreover,it may also contribute to the pathogenesis of PD.Based on summarizing the recent research process in microbiota-gut-brain axis and PD,it may be concluded that the suggestion of microbiota-gut-brain axis helps us better understand PD,and it provides a basis for using gut microbiota modification as a promising option to treat PD or reduce the risk of PD.关键词
帕金森病/肠道微生物/微生物-肠-脑轴/胃肠功能失调Key words
Parkinson disease/Gut microbiota/Microbiota-gut-brain axis/Gastrointestinal dysfunction分类
医药卫生引用本文复制引用
关小雪,承欧梅,王雨婵..微生物-肠-脑轴与帕金森病研究进展[J].中国全科医学,2017,20(24):3051-3055,5.
