中国畜牧兽医2017，Vol.44Issue(7)：2139-2146,8.DOI:10.16431/j.cnki.1671-7236.2017.07.033
非洲猪瘟病毒的分子病原学及致病机理研究进展
Research Progress on Molecular Etiology and Pathogenesis for African Swine Fever Virus
摘要
Abstract
African swine fever (ASF) is a devastating disease caused by African swine fever virus (ASFV), characterized by acute feature, high fever, high mortality and other characteristics.ASF mainly outbreaks in African, Eastern Europe countries, Russia and Caucasus region.At present, there are no vaccine available and effective control strategies against ASFV spread, therefore, ASF has a serious impact on the pig industry in the affected countries.The major target cells of the virus are swine reticuloendothelial cells and monocyte-macrophage cells.ASFV can result in apoptosis and affect the host''s immune system, and then show the characteristics of the corresponding disease.ASFV has the characteristics of large genome, more genotype and more variability.In this paper, the molecular etiology and pathogenesis of ASFV are reviewed, so as to provide theoretical basis for prevention and control of ASF.关键词
非洲猪瘟病毒/分子病原学/宿主/致病机理Key words
African swine fever virus (ASFV)/molecular etiology/host/pathogenesis分类
农业科技引用本文复制引用
欧云文,阎传忠,张杰,马炳,代军飞,张永光,贾宁..非洲猪瘟病毒的分子病原学及致病机理研究进展[J].中国畜牧兽医,2017,44(7):2139-2146,8.基金项目
国家国际合作项目(2012DFG31890) （2012DFG31890）
国家自然科学基金(31072143) （31072143）
