中国畜牧杂志2017,Vol.53Issue(7):13-17,5.DOI:10.19556/j.0258-7033.2017-07-013
抗氧化剂对精子质量影响的研究进展
Research Progress on Antioxidant Effect of on Sperm Quality
摘要
Abstract
Animal husbandry technology introduced in vitro fertilization to increase the utilization rate of genetically and phenotypically improve sire and to obtain high number of good quality embryos.One of the key factors of successful in vitro fertilization is semen preservation.cryopreservation is one of the best method for long-term preservation of semen.However preservation easily produce oxidative stress which is harmful for sperm.One of the main reason for this is that in vitro sperm lack the oxidant-antioxidant system protection of the body;Second reason is that the preservation process stimulates the overproduction of reactive oxygen.Both condition weaken sperm antioxidant ability and lead to structural and functional damage of the sperm.One of the key factors of oxidative stress is reactive oxygen species(ROS),which affect the quality of sperm,reduce the survival rate of embryos and decline the animal reproduction ability.To solve this problem,scientifically a large number of improvement measures have been studied such as adding antioxidants,improving conditions for semen storage environment,or both etc.At present,in the field of in vitro fertilization antioxidant drug has made a lot of new breakthroughs,but oxidative damage with sperm has not been fully solved.In this paper,we summarized the antioxidative effect on semen preservation.关键词
精子/体外受精/氧化应激/抗氧化剂Key words
Sperm/in vitro fertilization/Oxidative stress/Antioxidant分类
农业科技引用本文复制引用
周晶,方南洙,李钟淑,徐礼杰,李福俊..抗氧化剂对精子质量影响的研究进展[J].中国畜牧杂志,2017,53(7):13-17,5.基金项目
国家自然科学基金项目(31360546) (31360546)