中国畜牧杂志2017，Vol.53Issue(7)：44-48,5.DOI:10.19556/j.0258-7033.2017-07-044
IGFBP3基因内含子2多态性及其与猪主要生长性状的关联分析
The Polymorphism of IGFBP3 Intron 2 and Its Relationship with the Main Growth Traits of Pigs
摘要
Abstract
There is a relationship between the Insulin-like Growth Factor Binding Proteins (IGFBPs) and animals' growth and development.This research aimed to study the polymorphism of IGFBP3 and its relationship with pig growth characteristics.The method of PCR-RFLP was used to study the intron 2 of IGFBP3 of Landrace,Duroc and Landrace pigs.The influence ofIGFBP3 gene type to pig body length,body height,lean meat rate,back fat,muscle thickness,0～100 kg gain weight,30～100 kg and 100 kg gain weight growth traits were analyzed.The results showed that there were 417 bps for the intron 2 of IGFBP3,and the polymorphism of A307G affected the pig growth.The three pigs with IGFBP3 gene heterozygous AG genotype were dominant.Duroc and Landrace were deviated from Hardy-Weinberg one quilibrium at the site (P＜0.01).The IGFBP3 gene PIC showed moderate polymorphism in the three varieties of pig (0.34～0.37).The GG genotype of IGFBP3 gene had greatly influence in the body height (P=0.068) and lean meat rate (P=0.058) in large white.It had greatly influenced in the lean meat rate (P=0.099) and muscle thickness (P=0.079) of Duroc.The effect to weight gain at 0-100 kg were close to significant level in Landrace (P=0.08).This is showed that the GG genotype pig had the characteristics of higher body height and faster growth.It could suffer a suggestion for pig genetics and breeding.关键词
猪/IGFBP3/PCR-RFLP/关联分析Key words
Pig/IGFBP3/PCR-RFLP/Association analysis分类
农业科技引用本文复制引用
宋玉芹,于光辉,王建琳,张灿,张廷荣..IGFBP3基因内含子2多态性及其与猪主要生长性状的关联分析[J].中国畜牧杂志,2017,53(7):44-48,5.基金项目
山东省现代农业产业技术体系生猪创新团队(SDAIT-08-13) （SDAIT-08-13）
