中国医院用药评价与分析2017,Vol.17Issue(7):909-910,913,3.DOI:10.14009/j.issn.1672-2124.2017.07.016
中药联合头孢哌酮舒巴坦钠治疗肺癌化疗后肺部感染的疗效观察
Observation on Efficacy of Traditional Chinese Medicine Combined with Cefoperazone Sulbatam Sodium in Treatment of Pulmonary Infection After Chemotherapy of Lung Cancer
宋鸿 1屈焱 1常忠莲2
作者信息
- 1. 北京市石景山医院药剂科,北京 100043
- 2. 北京市石景山医院中医科,北京100043
- 折叠
摘要
Abstract
OBJECTIVE:To probe into the clinical efficacy of traditional Chinese medicine combined with cefoperazone sulbatam sodium in treatment of pulmonary infection after chemotherapy of lung cancer. METHODS:76 lung cancer patients with pulmonary infection after chemotherapy admitted into Beijing Shijingshan Hospital from Jan. 2015 to May 2016 were selected and divided into observation group and control group via random number table, with 38 cases in each. The control group was treated with cefoperazone sulbatam sodium, while the observation group was given decoction of traditional Chinese medicine based on the control group. The clinical efficacy, remission time of coughing and expectoration, remission time of fever, improvement time of lung rales and hospital stays of two groups were observed, the differences of pulmonary function indices and karnofsky performance status (KPS) of two groups before and after treatment were compared. RESULTS:The total effective rate of observation group was significantly higher than that of the control group; after treatment, the KPS, forced expiratory volume in 1 second and forced vital capacity of observation group were significantly higher than those of the control group, the remission time of coughing and expectoration, remission time of fever, improvement time of lung rales and hospital stays of observation group were significantly shorter than those of the control group, with statistically significant difference (P<0.05). CONCLUSIONS:The efficacy of traditional Chinese medicine combined with cefoperazone sulbatam sodium in treatment of pulmonary infection after chemotherapy of lung cancer is remarkable, which can effectively improve clinical symptoms and pulmonary functions, and shorten hospital stays.关键词
中药/头孢哌酮舒巴坦钠/肺癌/化疗后/肺部感染/临床疗效Key words
Traditional Chinese medicine/Cefoperazone sulbatam sodium/Lung cancer/After chemotherapy/Pulmonary infection/Clinical efficacy分类
医药卫生引用本文复制引用
宋鸿,屈焱,常忠莲..中药联合头孢哌酮舒巴坦钠治疗肺癌化疗后肺部感染的疗效观察[J].中国医院用药评价与分析,2017,17(7):909-910,913,3.