中国医院用药评价与分析2017,Vol.17Issue(7):991-993,3.DOI:10.14009/j.issn.1672-2124.2017.07.043
731张门诊超说明书用药处方点评与分析
Comment and Analysis on 731 Off-label Drug Use Prescriptions of Outpatient
郑明贵 1姚忠文 1张红霞 1熊变娥1
作者信息
- 1. 黔南州人民医院药剂科,贵州 都匀 558000
- 折叠
摘要
Abstract
OBJECTIVE:To investigate in off-label drug use for outpatients in People`s Hospital of Qiannan (hereinafter referred to as "our hospital"), so as to provide references for formulating administrative regulations of off-label drug use, and promote clinical rational and legal drug application. METHODS:4 days of prescriptions of outpatient (included emergency department) in our hospital were extracted each month in 2016, a total of 41 472 prescriptions were analyzed strictly according to dispensatories in terms of drug use indications, dosage, administration methods or routes, commended users, etc. RESULTS:Of 41 472 prescriptions, there were 731 off-label drug use prescriptions (accounted for 1.76%), mainly included over-indications, over-dosage, off-routes or off-methods, off-commended users; a total of 29 drugs were involved, the top 3 were respectively gentamicin sulfate injection,chymotrypsin for Injection,dexamethasone injection. CONCLUSIONS:Relevant administrative regulations of off-label drug use should be further improved, diagnosis and treatment of clinicians should be specified and prescription examining and verifying should be reinforced, so as to reduce irrational off-label drug use.关键词
门诊处方/超说明书用药/调查分析Key words
Prescriptions of outpatient/Off label drug use/Investigation and analysis分类
医药卫生引用本文复制引用
郑明贵,姚忠文,张红霞,熊变娥..731张门诊超说明书用药处方点评与分析[J].中国医院用药评价与分析,2017,17(7):991-993,3.