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基于体外细胞模型的霉菌毒素毒性评价

邱思奇 徐贞贞 沈红 杨曙明 陈爱亮 赵燕

动物营养学报2017,Vol.29Issue(8):2665-2675,11.
动物营养学报2017,Vol.29Issue(8):2665-2675,11.DOI:10.3969/j.issn.1006-267x.2017.08.008

基于体外细胞模型的霉菌毒素毒性评价

Evaluation of Mycotoxin Toxicity Based on Cell Model in Vitro

邱思奇 1徐贞贞 2沈红 1杨曙明 2陈爱亮 1赵燕1

作者信息

  • 1. 中国农业科学院农业质量标准与检测技术研究所,农业部农产品质量安全重点实验室,北京 100081
  • 2. 北京农学院动物科学技术学院,北京 102206
  • 折叠

摘要

Abstract

Mycotoxins are secondary metabolites produced by various fungi, which are widely found in food and feed. The contamination of mycotoxins on food and feed will result a large risk in livestock production and quality and safety of animal products. It is necessary to study the toxic mechanism of mycotoxins in order to e-valuating the risk of food and feed safety. As a commonly used method in vitro, cell model is widely used in toxicology research. This paper reviews general property, toxicity and toxic mechanism of aflatoxin B1, ochra-toxin A, deoxynivalenol, zearalenone and patulin based on cell model in vitro.

关键词

霉菌毒素/毒性/细胞模型

Key words

mycotoxin/toxicity/cell model

分类

农业科技

引用本文复制引用

邱思奇,徐贞贞,沈红,杨曙明,陈爱亮,赵燕..基于体外细胞模型的霉菌毒素毒性评价[J].动物营养学报,2017,29(8):2665-2675,11.

基金项目

国家自然科学基金青年科学基金项目(31401666) (31401666)

中央级公益性科研院所基本科研业务费专项(1610072016014) (1610072016014)

动物营养学报

OA北大核心CSCDCSTPCD

1006-267X

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