动物营养学报2017，Vol.29Issue(8)：2843-2850,8.DOI:10.3969/j.issn.1006-267x.2017.08.029
玉米赤霉烯酮对断奶小母猪生产性能、 血清抗氧化功能和免疫功能的影响
Effects of Zearalenone on Production Performance, Serum Antioxidant Capacity and Immune Function of Weaning Gilts
摘要
Abstract
The aim of the present study was to investigate the effects of diet polluted by different levels of zearalenone ( ZEA) on performance, serum antioxidant capacity, serum antibody levels and lymphocyte prolif-eration rate of weaning gilts. Forty healthy weaning piglets ( Duroc × Landrace × Large white) were allocated into 4 groups according to age [(35±1) days of age] and average body weight [(14.01±0.86) kg]. Piglets were fed a basal diet supplemented with 0 ( Control) , 0. 5, 1. 0 and 1. 5 mg/kg ZEA, respectively, and the measured values of ZEA were 0 mg/kg, ( 0. 52 ± 0. 07 ) mg/kg, ( 1. 04 ± 0. 03 ) mg/kg and ( 1. 51 ± 0.13) mg/kg, respectively. The adaptation period lasted for 10 days and the trial period lasted for 35 days. The results showed as follows: average daily feed intake, average daily gain and feed to gain ratio ( F/G) of weaning piglets were not significantly affected by dietary ZEA ( P>0.05) . Compared with control group, ser-um glutathione peroxidase ( GSH-Px) activity in 0.5, 1.0 and 1.5 mg/kg ZEA groups, antibody levels of clas-sical swine fever virus in 1.0 and 1.5 mg/kg ZEA groups and herpes virus in 1.5 mg/kg ZEA group, and lym-phocyte proliferation rate in peripheral blood in 1. 0 and 1. 5 mg/kg ZEA groups were significantly decreased (P<0.05), however, serum malondialdehyde (MDA) content in 0.5, 1.0 and 1.5 mg/kg ZEA groups was significantly increased ( P<0.05) . With the increase of ZEA level in diet for weaning gilts, feed to gain ratio showed a linear decreasing trend ( P=0.075) , serum activities of GSH-Px, superoxide dismutase ( SOD) , se-rum antibody levels of viruses ( classical swine fever virus, herpes virus and porcine reproductive and respirato-ry syndrome virus) and peripheral blood lymphocyte proliferation rate in peripheral blood showed linear decrea-ses ( P<0.05) , and serum MDA showed a linear increase ( P<0.05) . Thus, ZEA at 0.5 mg/kg is sufficient to induce oxidative stress in gilts, and ZEA at 1.0 mg/kg can significantly reduce both the specific humoral and cellular immune function of weaning gilts.关键词
玉米赤霉烯酮/断奶小母猪/生产性能/谷胱甘肽过氧化物酶/丙二醛/抗体水平/淋巴细胞增殖率Key words
zearalenone/weaning gilts/growth performance/glutathione peroxidase/malondialdehyde/anti-body level/lymphocyte proliferation rate分类
农业科技引用本文复制引用
杨立杰,王淑静,杨维仁,黄丽波,刘法孝,姜淑贞,杨在宾..玉米赤霉烯酮对断奶小母猪生产性能、 血清抗氧化功能和免疫功能的影响[J].动物营养学报,2017,29(8):2843-2850,8.基金项目
国家自然科学基金(31572441) （31572441）
山东省现代农业产业技术体系生猪创新团队建设项目(SDAIT-08-04) （SDAIT-08-04）
