海南医学院学报2017,Vol.23Issue(12):1627-1629,3.DOI:10.13210/j.cnki.jhmu.20170801.001
连续血浆滤过吸附与连续血液透析改善ICU脓毒血症患者免疫水平效果分析
Clinical effects investigation of continuous plasma filtration with adsorption and continuous hematodialysis on improving the immune level of patients with sepsis in ICU
杨远征 1胡志华 1邓小彦 1冼丽娜1
作者信息
- 1. 海南医学院第一附属医院重症医学科,海南 海口 570102
- 折叠
摘要
Abstract
Objective: To investigate the clinical effects of continuous plasma filtration with adsorption and continuous hematodialysis on improving the immune level of patients with sepsis in ICU.Methods: A total of 80 patients with sepsis were randomly divided into study group and control group, 40 patients in each group.All the patients were treated by routine treatment.Patients in study group were treated by continuous plasma filtration with adsorption and patients in control group were treated by continuous hematodialysis.The blood samples were collected before and after treatment.The immune cell level, inflammatory factors level, APACHE Ⅱ score and death rate were compared between two groups.Results: All immune cell indexes were significantly improved in both groups(P<0.05, P<0.01).All immune cell indexes in study group were significantly better than those in control group, after treatment(P<0.05, P<0.01).All inflammatory factors were significantly decreased in both groups (P<0.05, P<0.01).All inflammatory factors in study group were significantly better than those in control group, after treatment (P<0.05, P<0.01).The APACHE Ⅱin study group was significantly better than that in control group, after treatment (P<0.01).The death rate in study group was significantly less than that in control group (P<0.05).Conclusion: Continuous plasma filtration with adsorption has a great clinical efficacy on patients with sepsis in ICU, which can improve the immune level and prognosis, makes it worth for clinical application.关键词
脓毒血症/连续血浆滤过吸附/连续血液透析/免疫/临床效果Key words
Sepsis/Continuous plasma filtration with adsorption/Continuous hematodalysis/Immune/Clinical effects分类
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杨远征,胡志华,邓小彦,冼丽娜..连续血浆滤过吸附与连续血液透析改善ICU脓毒血症患者免疫水平效果分析[J].海南医学院学报,2017,23(12):1627-1629,3.