分析化学2017，Vol.45Issue(8)：1143-1148,6.DOI:10.11895/j.issn.0253-3820.170049
直喷离子化质谱简单快速鉴别关木通
Simple and Rapid Differentiation of Mutong of Aristolochiaceae by Direct Spray Mass Spectrometry
摘要
Abstract
Direct spray mass spectrometry was used to simply and rapidly differentiate Mutong of Aristolochiaceae from other two kinds of Mutong medicinal materials (Lardizabalaceae and Ranunculacea) by analyzing the chemical profile of Mutong of Aristolochiaceae.A novel method for determination of magnoflorine content in Mutong of Aristolochiaceae was established.The results showed that Mutong of Aristolochiaceae could be identified according to the symbolic component, magnoflorine.Under positive ion mode, semi-quantitative result based on the signal strength ratio of magnoflorine and nuciferin was obtained by choosing nuciferin as an internal standard.The method showed good linear coefficient in the concentration range of 0.50-20.00 mg/L of magnoflorine.The limit of detection was 0.1 mg/L.The method was simple and fast, and could be used for direct and rapid in-situ analysis and identification of Mutong of Aristolochiaceae from other closely related Mutong herbal species without sample pre-treatment.The results were important for the quality control of Mutong herbal medicine.关键词
直喷离子化质谱/关木通/木兰花碱/马兜铃酸AKey words
Direct spray mass spectrometry/Mutong of Aristolochiaceae/Magnoflorine/Aristolochic acid A引用本文复制引用
张朝辉,谷陟欣,刘婧靖,陈应庄,陈波,马铭..直喷离子化质谱简单快速鉴别关木通[J].分析化学,2017,45(8):1143-1148,6.基金项目
本文系国家自然科学基金项目(Nos.21575040, 21275052)资助This work was supported by the National Natural Science Foundation of China (Nos.21575040, 21275052) （Nos.21575040, 21275052）
