中国妇幼健康研究2017,Vol.28Issue(8):982-984,3.DOI:10.3969/j.issn.1673-5293.2017.08.031
胎儿先天性心脏病20例尸体解剖临床病理分析
Clinical pathological analysis on autopsy results of 20 fetuses with congenital heart disease
摘要
Abstract
Objective To conduct pathological analysis on autopsy of 20 cases of fetal congenital heart disease (CHD) and review literature so as to improve understanding of heart malformation.Methods Twenty cases of CHD found in 312 cases of fetal autopsy performed in recent 10 years in Changzhou Maternal and Child Health Care Hospital were collected.Detailed autopsy and pathological microscopic observation was performed on them and literature was reviewed at the same time.Results In 312 cases of fetuses with pathological anatomy , 20 cases were diagnosed with CHD, among which 8 were male and 12 were female, with 12 cases of atrioventricular septal defect, 2 cases of simple ventricular septal defect, 10 cases associated with other malformations , 1 case of tricuspid stenosis and tricuspid incompetence, 2 cases of pulmonary stenosis with tricuspid incompetence and maldevelopment of left ventricle, 2 cases of aortic arch branch abnormality (4 branches), 1 case of pulmonary atresia with tricuspid stenosis, 1 case of pulmonary artery and aortic reverse with absent left subclavian artery and 1 case of complete endocardial cushion defect and persistent left superior vena cava.Conclusion Congenital heart disease has characteristics of complicated intracardiac and extracardiac malformations.Detailed autopsy is required in order to find every cardiovascular branch and ensure accurate diagnosis and to explore its possible pathogenesis.关键词
尸体解剖/胎儿心脏/先天性心脏病/病理解剖学特征Key words
autopsy/fetal heart/congenital heart disease (CHD)/pathologic anatomic features分类
医药卫生引用本文复制引用
欧阳俊,虞斌,贾赛玉..胎儿先天性心脏病20例尸体解剖临床病理分析[J].中国妇幼健康研究,2017,28(8):982-984,3.基金项目
江苏省常州市高层次卫生人才培养工程资助项目(2016CZLJ013),常州市科技支撑计划(社会发展)资助项目(CE20155055),江苏省常州市妇幼保健科研资助项目(F201444),常州市卫计委指导性科研资助项目(WZ201411) (2016CZLJ013)