临床与病理杂志2017，Vol.37Issue(6)：1153-1157,5.DOI:10.3978/j.issn.2095-6959.2017.06.013
早产儿血小板减少症与母亲胎盘病理特点的关系
Association between premature thrombocytopenia and placental pathology
摘要
Abstract
Objective:To investigate the association between premature thrombocytopenia and placental lesions.Methods:Cases included singleton premature infants admitted to the neonatal intensive care unit of Guangdong Women and Children's Hospital,Guangzhou Medical University from January 1,2015 to December 31,2015 with platelet counts 100×109/L.We selected a contemporaneous control group matched for gestational age.The frequency of fetal thrombotic vasculopathy,infarcts,cord insertion and histological inflammation were identified on retrospectively reviewed.Pearson Chi-Square Test was used to test for associations analyzation.Results:The average gestational age of the thrombocytopenia group (106 cases) and the control group (198 cases)was (31.74±2.10) weeks and (31.92±2.06) weeks,respectively.The birth weight of the preterm neonates in the control group [(1 763.59±429.36) g] Was higher than that of the experimental group [(1 659.72±422.21) g],the difference was statistically significant (P＜0.05).The rate of placental insufficiency (preeclampsia 17.9％and intrauterine growth retardation 9.4％) were higher than those in the control group (preeclampsia 6.1％,intrauterine growth retardation 2.5％);the difference was statistically significant (P＜0.05).There was no significant difference in the average placental weight between the 2 groups [(381.98± 107.10) g and (397.05± 114.28) g].The frequency of fetal thrombotic vasculopathy (23.6％) and placental infarcts (35.8％) in the thrombocytopenia group were higher,the difference was statistically significant (P＜0.05).The frequency of histological inflammation and umbilical cord torsion between the groups are not statistically significant (P＞0.05).Conclusion:Placental infarcts and poor fetal vascular lesions,but not histological inflammation,are associated with thrombocytopenia in the premature infants.关键词
早产儿/血小板减少症/胎盘病理Key words
premature/thrombocytopenia/placental lesions引用本文复制引用
钟秀明,张晓玲,李晖,杨杰..早产儿血小板减少症与母亲胎盘病理特点的关系[J].临床与病理杂志,2017,37(6):1153-1157,5.基金项目
广州市科技计划项目(201707010398).This work was supported by the Science and Technology Program of Guangzhou,China(201707010398). （201707010398）
