临床与病理杂志2017，Vol.37Issue(6)：1164-1170,7.DOI:10.3978/j.issn.2095-6959.2017.06.015
肺腺鳞癌临床特征与预后因素
Clinical features and prognostic factors of lung adenosquamous carcinoma
摘要
Abstract
Objective:To investigate the characteristics of lung adenosquamous carcinoma (ASC) and to analyze the prognostic factors.Methods:We retrospectively reviewed the clinical data and genetic state from 95 patients with ASC,and the survival rate was calculated by Kaplan-Meier method and log-rank test was used to compare the survival rates.Univariate and multivariate factors for survival were analyzed by COX proportional hazards regression model.Results:Ninety-five cases of ASC were mainly men,more than 60 years old and smoking patients predominant;COX univariate analysis revealed that gender,age,smoking history,EGFR gene status,ALK fusion gene status,stage,subtype patterns and subtype type were prognostic factors for ASC.COX multivariate analysis found that stage,subtype patterns and subtype type were independent prognostic factors for ASC (P＜0.05).Conclusion:ASC mainly occurred in men patients over 60 years old with smoking.Stage,subtype patterns and subtype type are the crucial prognostic factors for ASC.关键词
腺鳞癌/肺/EGFR基因/ALK基因/突变率/预后Key words
adenosquamous carcinoma/lung/EGFR gene/ALK gene/mutation rate/prognostic引用本文复制引用
徐振武,徐倩,许春伟,王文娴,庄武..肺腺鳞癌临床特征与预后因素[J].临床与病理杂志,2017,37(6):1164-1170,7.基金项目
国家临床重点专科建设项目(2013).This work was supported by the National Clinical Key Specialty Construction Program,China (2013). （2013）
