海南医学院学报2017，Vol.23Issue(13)：1791-1793,1797,4.DOI:10.13210/j.cnki.jhmu.20170809.032
肾病型肠内营养制剂对维持性血液透析合并营养不良患者营养状态、微炎症状态的影响
Effect of nephrotic enteral nutrition preparation on nutritional status and microinflammatory state in patients with maintenance hemodialysis complicated by malnutrition
摘要
Abstract
Objective:To study the effect of nephrotic enteral nutrition preparation on the nutritional status and microinflammatory state in patients with maintenance hemodialysis complicated by malnutrition.Methods:A total of 68 patients who received maintenance hemodialysis and had malnutrition in our hospital between January 2013 and July 2016 were collected and divided into control group (n=34) and observation group (n=34) according to random number table.Patients in control group received regular dietary intervention while observation group received nephrotic enteral nutrition preparation based on routine intervention.Nutritional status and microinflammatory state before and after intervention were compared between two groups of patients.Results:Before intervention,the differences in peripheral blood levels of protein indexes and trace elements as well as serum levels of inflammatory factors were not statistically significant between two groups of patients (P>0.05).After intervention,peripheral blood nutrition-related proteins TP,ALB,PA,Hb and TRF levels of observation group were significantly higher than those of control group (P<0.05);peripheral blood trace elements Zn and Fe levels were significantly higher than those of control group while Ca level was significantly lower than that of control group (P<0.05);serum inflammatory factors IL-6,hs-CRP and TNF-α levels were significantly lower than those of control group (P<0.05).Conclusions:Nephrotic enteral nutrition preparation can effectively optimize nutritional status and reduce microinflammation degree in patients with maintenance hemodialysis complicated by malnutrition.关键词
维持性血液透析/营养不良/肾病型肠内营养制剂/营养状态/微炎症状态Key words
Maintenance hemodialysis/Malnutrition/Nephrotic enteral nutrition preparation/Nutritional status/Microinflammatory state分类
医药卫生引用本文复制引用
兰传英,唐利..肾病型肠内营养制剂对维持性血液透析合并营养不良患者营养状态、微炎症状态的影响[J].海南医学院学报,2017,23(13):1791-1793,1797,4.基金项目
自贡市科技局课题项目(2013ZC27) （2013ZC27）
This study was supported by Science and Technology Bureau of Zigong City (Grant No.2013ZC27) （Grant No.2013ZC27）
