华西口腔医学杂志2017，Vol.35Issue(4)：413-418,6.DOI:10.7518/hxkq.2017.04.014
单光子发射计算机断层成像在诊断口腔癌颌骨侵犯中的价值:系统评价及Meta分析
Single-photon emission computed tomography for the diagnosis of mandibular invasion caused by oral cancers: a systematic review and Meta-analysis
摘要
Abstract
Objective This review aimed at assessing the diagnostic efficacy of contrast-enhanced single-photon emission computed tomography (SPECT) in the diagnosis of mandibular invasion by oral cancers. Methods Five databases were searched electronically on August 5, 2016. The reference lists of included studies were hand searched. Quality assessment was performed by two reviewers in duplicate with tools suggested by Cochrane's handbook. Furthermore, the data extraction of included studies was delivered. Meta-analysis was performed using STATA 11.0. Results Ten studies with 460 participants were included. One study had a low risk of bias, and two studies had a high risk of bias. The remaining seven studies had an unclear risk of bias. Meta-analysis results showed that SPECT had a pooled sensitivity of 0.99 [95% confidence interval=0.87-1.00]. Sensitivity was 0.99 on Q* point. The specificity of 0.61 and the area under summary receiver operating characteristic curve (SROC) were 0.93 [95% confidence interval=0.90-0.95]. The pooled positive likelihood ratio was 2.555. The negative likelihood ratio was 0.015. The diagnostic odd ratio was 5.115. Conclusion SPECT had high sensitivity, which became suitable for excluding bone invasion by oralcancers. However, its specificity was relatively low, indicating its limited capability in confirming diagnosis. Therefore, sur-geons should perform this method under certain conditions.关键词
单光子发射计算机断层成像/口腔癌/下颌骨/诊断/Meta分析Key words
single-photon emission computed tomography/mouth neoplasm/mandible/diagnosis/Meta-analysis分类
医药卫生引用本文复制引用
王晓念,罗奋娟,乔翔鹤,杨文宾,林洁,李春洁..单光子发射计算机断层成像在诊断口腔癌颌骨侵犯中的价值:系统评价及Meta分析[J].华西口腔医学杂志,2017,35(4):413-418,6.基金项目
2016年四川大学优秀青年学者基金(2082604194311)Outstanding Youth Foundation of Sichuan University in 2016 (2082604194311). （2082604194311）
