基础医学与临床2017，Vol.37Issue(7)：1051-1054,4.
坏死性凋亡与肿瘤
Necroptosis and tumor
摘要
Abstract
Necroptosis,it is activated by the formation of necrosome,is a way of programmed cell death that independent of the activation of caspase.Necroptosis is regulated by many factors,for example,RIPK1 can initiate necroptosis,but also inhibit necroptosis;caspase-8 is the key negative regulation factor of necroptosis;CHIP is a new regulation protein of necroptosis.Triggering necroptosis is a promising strategy to overcome apoptosis resistance in cancer.关键词
坏死性凋亡/RIPK/caspase-8/CHIP/肿瘤Key words
necroptosis/RIPK/caspase-8/CHIP/tumor分类
医药卫生引用本文复制引用
王莲子,李涛..坏死性凋亡与肿瘤[J].基础医学与临床,2017,37(7):1051-1054,4.基金项目
国家自然基金(30801088,81201488,81571572) （30801088,81201488,81571572）
